The latent phase of labor.

cervical remodeling cervical ripening collagen epidural anesthesia false labor initiation of labor labor latent phase morphine oxytocin prolonged latent phase therapeutic rest

Journal

American journal of obstetrics and gynecology
ISSN: 1097-6868
Titre abrégé: Am J Obstet Gynecol
Pays: United States
ID NLM: 0370476

Informations de publication

Date de publication:
05 2023
Historique:
received: 18 01 2022
revised: 07 04 2022
accepted: 11 04 2022
medline: 12 5 2023
pubmed: 28 3 2023
entrez: 27 3 2023
Statut: ppublish

Résumé

The latent phase of labor extends from the initiation of labor to the onset of the active phase. Because neither margin is always precisely identifiable, the duration of the latent phase often can only be estimated. During this phase, the cervix undergoes a process of rapid remodeling, which may have begun gradually weeks before. As a consequence of extensive changes in its collagen and ground substance, the cervix softens, becomes thinner and dramatically more compliant, and may dilate modestly. All of these changes prepare the cervix for the more rapid dilatation that will occur during the active phase to follow. For the clinician, it is important to recognize that the latent phase may normally extend for many hours. The normal limit for the duration of the latent phase should be considered to be approximately 20 hours in a nullipara and 14 hours in a multipara. Factors that have been associated with a prolonged latent phase include deficient prelabor or intrapartum cervical remodeling, excessive maternal analgesia or anesthesia, maternal obesity, and chorioamnionitis. Approximately 10% of women with a prolonged latent phase are actually in false labor, and their contractions eventually abate spontaneously. The management of a prolonged latent phase involves either augmenting uterine activity with oxytocin or providing a sedative-induced period of maternal rest. Both are equally effective in advancing the labor to active phase dilatation. A very long latent phase may be a harbinger of other labor dysfunctions.

Identifiants

pubmed: 36973092
pii: S0002-9378(22)00308-8
doi: 10.1016/j.ajog.2022.04.029
pii:
doi:

Substances chimiques

Oxytocin 50-56-6

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

S1017-S1024

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Wayne R Cohen (WR)

Department of Obstetrics and Gynecology, The University of Arizona College of Medicine, Tucson, AZ. Electronic address: cohenw@email.arizona.edu.

Emanuel A Friedman (EA)

Department of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Boston, MA.

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Classifications MeSH