Role of Direct Supervision in the Learning Curve of Descemet Membrane Endothelial Keratoplasty Surgery.


Journal

Cornea
ISSN: 1536-4798
Titre abrégé: Cornea
Pays: United States
ID NLM: 8216186

Informations de publication

Date de publication:
01 Jan 2024
Historique:
received: 15 11 2022
accepted: 26 02 2023
medline: 6 12 2023
pubmed: 25 4 2023
entrez: 25 4 2023
Statut: ppublish

Résumé

The aim of this study was to compare complication rates of Descemet membrane endothelial keratoplasty (DMEK) performed by directly supervised and nondirectly supervised corneal fellows. This study was a retrospective, comparative case series of DMEK surgeries performed by novice surgeons (less than 15 DMEK cases) with or without direct direct expert supervision. Patients who underwent surgery for Fuchs endothelial dystrophy or pseudophakic bullous keratopathy with a minimum follow-up of 12 weeks were included. Data on patients' demographics, surgical details, surgeon level, intraoperative and postoperative complications, and rate of rebubbling were collected. In this study, 41 nondirectly supervised and 48 directly supervised DMEK surgeries were included. At 6 months, 67.4% of eyes achieved a best-corrected visual acuity of ≤0.3 logMAR with no significant difference between groups ( P = 0.95). Intraoperative complications occurred in 22% of cases in the nondirect supervision group and 4.2% in the direct supervision group ( P = 0.02). Postoperative complications occurred in 9.8% of cases in the nondirect supervision group and 6.2% of cases in the direct supervision group ( P = 0.7). The rebubbling rate was comparable in the 2 groups (34.1% vs. 33.3%, P = 1.0). Five cases (12.2%), all from the nondirect supervision group, required secondary keratoplasty ( P = 0.02). The overall complication rate was significantly higher in the nondirect supervision group (31.7% vs. 10.4%, P = 0.03). Functional success can be achieved in directly supervised or nondirectly supervised DMEK surgery. However, nondirectly supervised DMEK surgery may associate with higher rates of complications.

Identifiants

pubmed: 37098113
doi: 10.1097/ICO.0000000000003278
pii: 00003226-202401000-00009
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

52-58

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

The authors have no funding or conflicts of interest to disclose.

Références

Annual Activity Report. ODT Clinical - NHS Blood and Transplant. 2022.
Parekh M, Romano D, Wongvisavavit R, et al. DMEK graft: one size does not fit all. Acta Ophthalmol (Copenh).2023;101:e14–e25.
Parekh M, Ruzza A, Romano V, et al. Descemet membrane endothelial keratoplasty learning curve for graft preparation in an Eye Bank using 645 donor corneas. Cornea. 2018;37:767–771.
Moramarco A, Romano V, Modugno RL, et al. Yogurt technique for descemet membrane endothelial keratoplasty graft preparation: early clinical outcomes. Cornea. 2023;42:27–31.
Hamzaoglu EC, Straiko MD, Mayko ZM, et al. The first 100 eyes of standardized descemet stripping automated endothelial keratoplasty versus standardized descemet membrane endothelial keratoplasty. Ophthalmology. 2015;122:2193–2199.
Dapena I, Ham L, Droutsas K, et al. Learning curve in Descemet's membrane endothelial keratoplasty: first series of 135 consecutive cases. Ophthalmology. 2011;118:2147–2154.
Borroni D, Rocha de Lossada C, Parekh M, et al. Tips, tricks, and guides in descemet membrane endothelial keratoplasty learning curve. J Ophthalmol. 2021;2021:1–9.
Stuart AJ, Romano V, Virgili G, et al. Descemet's membrane endothelial keratoplasty (DMEK) versus Descemet's stripping automated endothelial keratoplasty (DSAEK) for corneal endothelial failure. Cochrane Database Syst Rev. 2018;6:CD012097.
Guerra FP, Anshu A, Price MO, et al. Descemet's membrane endothelial keratoplasty: prospective study of 1-year visual outcomes, graft survival, and endothelial cell loss. Ophthalmology. 2011;118:2368–2373.
Peraza-Nieves J, Baydoun L, Dapena I, et al. Two-year clinical outcome of 500 consecutive cases undergoing descemet membrane endothelial keratoplasty. Cornea. 2017;36:655–660.
Quilendrino R, Rodriguez-Calvo de Mora M, Baydoun L, et al. Prevention and management of descemet membrane endothelial keratoplasty complications. Cornea. 2017;36:1089–1095.
Koo EH, Pineda R, Afshari N, et al. Learning descemet membrane endothelial keratoplasty: a survey of U.S. Corneal surgeons. Cornea. 2020;39:590–593.
Droutsas K, Petrak M, Melles GRJ, et al. A simple ex vivo model for teaching Descemet membrane endothelial keratoplasty. Acta Ophthalmol (Copenh). 2014;92:e362–e365.
Seitz B, Daas L, Bischoff-Jung M, et al. Anatomy-based DMEK Wetlab in Homburg/Saar: novel aspects of donor preparation and host maneuvers to teach descemet membrane endothelial keratoplasty. Clin Anat. 2018;31:16–27.
Vasquez Perez A, Liu C. Human ex vivo artificial anterior chamber model for practice DMEK surgery. Cornea. 2017;36:394–397.
Sáles CS, Straiko MD, Fernandez AA, et al. Partitioning an artificial anterior chamber with a latex Diaphragm to simulate anterior and posterior segment pressure dynamics: the “DMEK practice stage,” where surgeons can rehearse the “DMEK dance”. Cornea. 2018;37:263–266.
Khanam T. OP-7 Our experience of DMEK wet lab-training course as a precursor to starting DMEK service at NHS Trusts during COVID-19 pandemic in UK. BMJ Open Ophthalmol. 2022;7(suppl 1):A2.
Pereira NC, Gomes JÁP, Moriyama AS, et al. Descemet membrane endothelial keratoplasty outcomes during the initial learning curve of cornea fellows. Cornea. 2019;38:806–811.
Parekh M, Borroni D, Ruzza A, et al. A comparative study on different Descemet membrane endothelial keratoplasty graft preparation techniques. Acta Ophthalmol (Copenh). 2018;96:e718–e726.
Romano V, Pagano L, Gadhvi KA, et al. Clinical outcomes of pre-loaded ultra-thin DSAEK and pre-loaded DMEK. BMJ Open Ophthalmol. 2020;5(1):e000546.
Romano V, Kazaili A, Pagano L, et al. Eye bank versus surgeon prepared DMEK tissues: influence on adhesion and re-bubbling rate. Br J Ophthalmol. 2022;106:177–183.
Coco G, Pagano L, Borgia A, et al. Novel technique for Descemetorhexis under ophthalmic viscosurgical devices and air. Cornea. 2021;40:1215–1217.
Gerber-Hollbach N, Baydoun L, López EF, et al. Clinical outcome of rebubbling for graft detachment after descemet membrane endothelial keratoplasty. Cornea. 2017;36:771–776.
McKee HD, Jhanji V. Learning DMEK from YouTube. Cornea. 2017;36:1477–1479.
Debellemanière G, Guilbert E, Courtin R, et al. Impact of surgical learning curve in descemet membrane endothelial keratoplasty on visual acuity gain. Cornea. 2017;36:1–6.
Price MO, Giebel AW, Fairchild KM, et al. Descemet's membrane endothelial keratoplasty: prospective multicenter study of visual and refractive outcomes and endothelial survival. Ophthalmology. 2009;116:2361–2368.
Patel AS, Goshe JM, Srivastava SK, et al. Intraoperative optical coherence tomography-assisted descemet membrane endothelial keratoplasty in the DISCOVER study: first 100 cases. Am J Ophthalmol. 2020;210:167–173.
Crews JW, Price MO, Lautert J, et al. Intraoperative hyphema in Descemet membrane endothelial keratoplasty alone or combined with phacoemulsification. J Cataract Refractive Surg. 2018;44:198–201.
Parekh M, Leon P, Ruzza A, et al. Graft detachment and rebubbling rate in Descemet membrane endothelial keratoplasty. Surv Ophthalmol. 2018;63:245–250.

Auteurs

Alfredo Borgia (A)

Eye Unit, Humanitas-Gradenigo Hospital, Turin, Italy.
Department of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.

Giulia Coco (G)

Department of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Department of Clinical Science and Translational Medicine, University of Rome Tor Vergata, Rome, Italy.

Matteo Airaldi (M)

Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, Ophthalmology Clinic, University of Brescia, Italy.

Davide Romano (D)

Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, Ophthalmology Clinic, University of Brescia, Italy.
Eye Unit, University Hospitals of Leicester, NHS Trust, Leicester, United Kingdom; and.

Luca Pagano (L)

Department of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.

Francesco Semeraro (F)

Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, Ophthalmology Clinic, University of Brescia, Italy.

Nardine Menassa (N)

Department of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Department of Eye and Vision Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom.

Kunal A Gadhvi (KA)

Department of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Department of Eye and Vision Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom.

Stephen B Kaye (SB)

Department of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Department of Eye and Vision Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom.

Vito Romano (V)

Department of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, Ophthalmology Clinic, University of Brescia, Italy.
Department of Eye and Vision Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom.

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