De novo design of protein interactions with learned surface fingerprints.

Humans Proteins / chemistry Proteomics Protein Binding Protein Interaction Maps Deep Learning Computer Simulation Binding Sites Synthetic Biology

Journal

Nature

ISSN: 1476-4687

Titre abrégé: Nature

Pays: England

ID NLM: 0410462

Informations de publication

Date de publication:
May 2023

Historique:

received: 16 06 2022

accepted: 21 03 2023

medline: 5 5 2023

pubmed: 27 4 2023

entrez: 26 4 2023

Statut: ppublish

Résumé

Physical interactions between proteins are essential for most biological processes governing life

Identifiants

DOI: 10.1038/s41586-023-05993-x PMID: 37100904 PMC: PMC10131520

pubmed: 37100904

doi: 10.1038/s41586-023-05993-x

pii: 10.1038/s41586-023-05993-x

pmc: PMC10131520

doi:

Substances chimiques

Proteins 0

spike protein, SARS-CoV-2 0

CTLA4 protein, human 0

CD274 protein, human 0

PDCD1 protein, human 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

176-184

Informations de copyright

Références

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