Pablo Gainza

Affiliations

Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

ORCID: http://orcid.org/0000-0001-9197-0982

Publications (12)

Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning.

Nature biomedical engineering

Avec: Derek M Mason , Simon Friedensohn , Cédric R Weber , Christian Jordi , Bastian Wagner , Simon M Meng , Roy A Ehling , Lucia Bonati , Jan Dahinden , Pablo Gainza , Bruno E Correia , Sai T Reddy

Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus.

PLoS computational biology

Avec: Siyu Wang , Stephanie M Reeve , Graham T Holt , Adegoke A Ojewole , Marcel S Frenkel , Pablo Gainza , Santosh Keshipeddy , Vance G Fowler , Dennis L Wright , Bruce R Donald

From Thalidomide to Rational Molecular Glue Design for Targeted Protein Degradation.

Annual review of pharmacology and toxicology

Avec: Vladas Oleinikovas , Pablo Gainza , Thomas Ryckmans , Bernhard Fasching , Nicolas H Thomä

A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy.

Nature biotechnology

Avec: Greta Giordano-Attianese , Pablo Gainza , Elise Gray-Gaillard , Elisabetta Cribioli , Sailan Shui , Seonghoon Kim , Mi-Jeong Kwak , Sabrina Vollers , Angel De Jesus Corria Osorio , Patrick Reichenbach , Jaume Bonet , Byung-Ha Oh , Melita Irving , George Coukos , Bruno E Correia

Rational Design of Chemically Controlled Antibodies and Protein Therapeutics.

ACS chemical biology

Avec: Anthony Marchand , Lucia Bonati , Sailan Shui , Leo Scheller , Pablo Gainza , Stéphane Rosset , Sandrine Georgeon , Li Tang , Bruno E Correia

De novo design of protein interactions with learned surface fingerprints.

Nature

Avec: Pablo Gainza , Sarah Wehrle , Alexandra Van Hall-Beauvais , Anthony Marchand , Andreas Scheck , Zander Harteveld , Stephen Buckley , Dongchun Ni , Shuguang Tan , Freyr Sverrisson , Casper Goverde , Priscilla Turelli , Charlène Raclot , Alexandra Teslenko , Martin Pacesa , Stéphane Rosset , Sandrine Georgeon , Jane Marsden , Aaron Petruzzella , Kefang Liu , Zepeng Xu , Yan Chai , Pu Han , George F Gao , Elisa Oricchio , Beat Fierz , Didier Trono , Henning Stahlberg , Michael Bronstein , Bruno E Correia

Rules and mechanisms governing G protein coupling selectivity of GPCRs.

Cell reports

Avec: Ikuo Masuho , Ryoji Kise , Pablo Gainza , Ee Von Moo , Xiaona Li , Ryosuke Tany , Hideko Wakasugi-Masuho , Bruno E Correia , Kirill A Martemyanov

Dual ON/OFF-switch chimeric antigen receptor controlled by two clinically approved drugs.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Greta Maria Paola Giordano Attianese , Sailan Shui , Elisabetta Cribioli , Melanie Triboulet , Leo Scheller , Morteza Hafezi , Patrick Reichenbach , Pablo Gainza , Sandrine Georgeon , Bruno E Correia , Melita Irving

Author Correction: A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy.

Nature biotechnology

Avec: Greta Giordano-Attianese , Pablo Gainza , Elise Gray-Gaillard , Elisabetta Cribioli , Sailan Shui , Seonghoon Kim , Mi-Jeong Kwak , Sabrina Vollers , Angel De Jesus Corria Osorio , Patrick Reichenbach , Jaume Bonet , Byung-Ha Oh , Melita Irving , George Coukos , Bruno E Correia

Deciphering interaction fingerprints from protein molecular surfaces using geometric deep learning.

Nature methods

Avec: P Gainza , F Sverrisson , F Monti , E Rodolà , D Boscaini , M M Bronstein , B E Correia

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen.

PLoS biology

Avec: Fabian Sesterhenn , Marie Galloux , Sabrina S Vollers , Lucia Csepregi , Che Yang , Delphyne Descamps , Jaume Bonet , Simon Friedensohn , Pablo Gainza , Patricia Corthésy , Man Chen , Stéphane Rosset , Marie-Anne Rameix-Welti , Jean-François Éléouët , Sai T Reddy , Barney S Graham , Sabine Riffault , Bruno E Correia

A rational blueprint for the design of chemically-controlled protein switches.

Nature communications

Avec: Sailan Shui , Pablo Gainza , Leo Scheller , Che Yang , Yoichi Kurumida , Stéphane Rosset , Sandrine Georgeon , Raphaël B Di Roberto , Rocío Castellanos-Rueda , Sai T Reddy , Bruno E Correia

Réseau de co-auteurs

Bruno E Correia 9 collaborations

Sailan Shui 5 collaborations

Stéphane Rosset 4 collaborations

Sandrine Georgeon 4 collaborations

Sai T Reddy 3 collaborations

Elisabetta Cribioli 3 collaborations

Patrick Reichenbach 3 collaborations

Jaume Bonet 3 collaborations

Melita Irving 3 collaborations

Leo Scheller 3 collaborations

Simon Friedensohn 2 collaborations

Lucia Bonati 2 collaborations

Greta Giordano-Attianese 2 collaborations

Elise Gray-Gaillard 2 collaborations

Seonghoon Kim 2 collaborations

Mi-Jeong Kwak 2 collaborations

Sabrina Vollers 2 collaborations

Angel De Jesus Corria Osorio 2 collaborations

Byung-Ha Oh 2 collaborations

George Coukos 2 collaborations

Anthony Marchand 2 collaborations

Che Yang 2 collaborations

Derek M Mason 1 collaboration

Cédric R Weber 1 collaboration

Christian Jordi 1 collaboration

Bastian Wagner 1 collaboration

Simon M Meng 1 collaboration

Roy A Ehling 1 collaboration

Jan Dahinden 1 collaboration

Siyu Wang 1 collaboration

Stephanie M Reeve 1 collaboration

Graham T Holt 1 collaboration

Adegoke A Ojewole 1 collaboration

Marcel S Frenkel 1 collaboration

Santosh Keshipeddy 1 collaboration

Vance G Fowler 1 collaboration

Dennis L Wright 1 collaboration

Bruce R Donald 1 collaboration

Vladas Oleinikovas 1 collaboration

Thomas Ryckmans 1 collaboration

Bernhard Fasching 1 collaboration

Nicolas H Thomä 1 collaboration

Li Tang 1 collaboration

Sarah Wehrle 1 collaboration

Alexandra Van Hall-Beauvais 1 collaboration

Andreas Scheck 1 collaboration

Zander Harteveld 1 collaboration

Stephen Buckley 1 collaboration

Dongchun Ni 1 collaboration

Shuguang Tan 1 collaboration

Freyr Sverrisson 1 collaboration

Casper Goverde 1 collaboration

Priscilla Turelli 1 collaboration

Charlène Raclot 1 collaboration

Alexandra Teslenko 1 collaboration

Martin Pacesa 1 collaboration

Jane Marsden 1 collaboration

Aaron Petruzzella 1 collaboration

Kefang Liu 1 collaboration

Zepeng Xu 1 collaboration

Yan Chai 1 collaboration

Pu Han 1 collaboration

George F Gao 1 collaboration

Elisa Oricchio 1 collaboration

Beat Fierz 1 collaboration

Didier Trono 1 collaboration

Henning Stahlberg 1 collaboration

Michael Bronstein 1 collaboration

Ikuo Masuho 1 collaboration

Ryoji Kise 1 collaboration

Ee Von Moo 1 collaboration

Xiaona Li 1 collaboration

Ryosuke Tany 1 collaboration

Hideko Wakasugi-Masuho 1 collaboration

Kirill A Martemyanov 1 collaboration

Greta Maria Paola Giordano Attianese 1 collaboration

Melanie Triboulet 1 collaboration

Morteza Hafezi 1 collaboration

P Gainza 1 collaboration

F Sverrisson 1 collaboration

F Monti 1 collaboration

E Rodolà 1 collaboration

D Boscaini 1 collaboration

M M Bronstein 1 collaboration

B E Correia 1 collaboration

Fabian Sesterhenn 1 collaboration

Marie Galloux 1 collaboration

Sabrina S Vollers 1 collaboration

Lucia Csepregi 1 collaboration

Delphyne Descamps 1 collaboration

Patricia Corthésy 1 collaboration

Man Chen 1 collaboration

Marie-Anne Rameix-Welti 1 collaboration

Jean-François Éléouët 1 collaboration

Barney S Graham 1 collaboration

Sabine Riffault 1 collaboration

Yoichi Kurumida 1 collaboration

Raphaël B Di Roberto 1 collaboration

Rocío Castellanos-Rueda 1 collaboration