Essential Oils from Mediterranean Plants Inhibit In Vitro Monocyte Adhesion to Endothelial Cells from Umbilical Cords of Females with Gestational Diabetes Mellitus.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
13 Apr 2023
Historique:
received: 16 01 2023
revised: 11 04 2023
accepted: 12 04 2023
medline: 1 5 2023
pubmed: 28 4 2023
entrez: 28 4 2023
Statut: epublish

Résumé

Essential oils (EOs) are mixtures of volatile compounds belonging to several chemical classes derived from aromatic plants using different distillation techniques. Recent studies suggest that the consumption of Mediterranean plants, such as anise and laurel, contributes to improving the lipid and glycemic profile of patients with diabetes mellitus (DM). Hence, the aim of the present study was to investigate the potential anti-inflammatory effect of anise and laurel EOs (AEO and LEO) on endothelial cells isolated from the umbilical cord vein of females with gestational diabetes mellitus (GDM-HUVEC), which is a suitable in vitro model to reproduce the pro-inflammatory phenotype of a diabetic endothelium. For this purpose, the Gas Chromatographic/Mass Spectrometric (GC-MS) chemical profiles of AEO and LEO were first analyzed. Thus, GDM-HUVEC and related controls (C-HUVEC) were pre-treated for 24 h with AEO and LEO at 0.025%

Identifiants

pubmed: 37108387
pii: ijms24087225
doi: 10.3390/ijms24087225
pmc: PMC10138528
pii:
doi:

Substances chimiques

Oils, Volatile 0
NF-kappa B 0
Vascular Cell Adhesion Molecule-1 0
Tumor Necrosis Factor-alpha 0
Intercellular Adhesion Molecule-1 126547-89-5

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Valeria Schiavone (V)

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Center for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

Tea Romasco (T)

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Center for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

Nadia Di Pietrantonio (N)

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Center for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

Stefania Garzoli (S)

Department of Pharmaceutical Chemistry and Technology, Sapienza University of Rome, 00185 Roma, Italy.

Carola Palmerini (C)

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Center for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

Pamela Di Tomo (P)

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Center for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

Caterina Pipino (C)

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Center for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

Domitilla Mandatori (D)

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Center for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

Rossella Fioravanti (R)

Department of Pharmaceutical Chemistry and Technology, Sapienza University of Rome, 00185 Roma, Italy.

Elena Butturini (E)

Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, 37129 Verona, Italy.

Manuela Sabatino (M)

Rome Center for Molecular Design-RCMD, Department of Pharmaceutical Chemistry and Technology, Sapienza University of Rome, 00185 Roma, Italy.

Maria Pompea Antonia Baldassarre (MPA)

Center for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Department of Medicine and Aging Sciences, "G. d'Annunzio" University Chieti-Pescara, 66100 Chieti, Italy.

Rino Ragno (R)

Rome Center for Molecular Design-RCMD, Department of Pharmaceutical Chemistry and Technology, Sapienza University of Rome, 00185 Roma, Italy.

Assunta Pandolfi (A)

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Center for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

Natalia Di Pietro (N)

Department of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Center for Advanced Studies and Technology-CAST, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

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