Prodrug Strategies for the Development of β-l-5-((


Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
25 05 2023
Historique:
medline: 26 5 2023
pubmed: 4 5 2023
entrez: 4 5 2023
Statut: ppublish

Résumé

Varicella zoster virus (VZV) establishes lifelong infection after primary disease and can reactivate. Several drugs are approved to treat VZV diseases, but new antivirals with greater potency are needed. Previously, we identified β-l-5-((

Identifiants

pubmed: 37140467
doi: 10.1021/acs.jmedchem.3c00545
pmc: PMC10226046
doi:

Substances chimiques

Uracil 56HH86ZVCT
Prodrugs 0
Dioxolanes 0
Antiviral Agents 0
Amino Acids 0
Phosphates 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7038-7053

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Auteurs

Uma S Singh (US)

Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.

Ananda K Konreddy (AK)

Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.

Yugandhar Kothapalli (Y)

Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.

Dongmei Liu (D)

State University of New York, Upstate Medical University, Syracuse, New York 13210, United States.

Megan G Lloyd (MG)

State University of New York, Upstate Medical University, Syracuse, New York 13210, United States.

Vidya Annavarapu (V)

Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.

Catherine A White (CA)

Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.

Michael G Bartlett (MG)

Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.

Jennifer F Moffat (JF)

State University of New York, Upstate Medical University, Syracuse, New York 13210, United States.

Chung K Chu (CK)

Department of Pharmaceutical and Biomedical Science, College of Pharmacy, University of Georgia, Athens, Georgia 30602, United States.

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Classifications MeSH