The effect of chondroitin sulfate concentration and matrix stiffness on chondrogenic differentiation of mesenchymal stem cells.
Journal
Biomaterials science
ISSN: 2047-4849
Titre abrégé: Biomater Sci
Pays: England
ID NLM: 101593571
Informations de publication
Date de publication:
27 Jun 2023
27 Jun 2023
Historique:
medline:
29
6
2023
pubmed:
9
5
2023
entrez:
9
5
2023
Statut:
epublish
Résumé
Chondroitin sulfate (CS), a glycosaminoglycan of native cartilage, has shown its potential in promoting chondrogenesis of mesenchymal stem cells (MSCs), whereas the effect of matrix stiffness in a CS-containing 3D environment on chondrogenesis is still poorly understood. Herein, this study aimed at assessing the effect of CS concentration and stiffness of CS-containing hydrogels on the chondrogenesis of MSCs. Hydrogels composed of 6% (w/v) gelatin methacryloyl (GelMA) and three concentrations,
Substances chimiques
Chondroitin Sulfates
9007-28-7
Hydrogels
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM