Recombination between heterologous human acrocentric chromosomes.

Humans Centromere / genetics Chromosomes, Human / genetics DNA, Ribosomal / genetics Recombination, Genetic / genetics Translocation, Genetic / genetics Cytogenetics Telomere / genetics

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
05 2023
Historique:
received: 15 08 2022
accepted: 17 03 2023
medline: 12 5 2023
pubmed: 11 5 2023
entrez: 10 5 2023
Statut: ppublish

Résumé

The short arms of the human acrocentric chromosomes 13, 14, 15, 21 and 22 (SAACs) share large homologous regions, including ribosomal DNA repeats and extended segmental duplications

Identifiants

DOI: 10.1038/s41586-023-05976-y PMID: 37165241 PMC: PMC10172130
pubmed: 37165241
doi: 10.1038/s41586-023-05976-y
pii: 10.1038/s41586-023-05976-y
pmc: PMC10172130
doi:

Substances chimiques

DNA, Ribosomal 0

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

335-343

Subventions

Organisme : NHGRI NIH HHS
ID : U41 HG010972
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA266339
Pays : United States
Organisme : NHGRI NIH HHS
ID : U24 HG010262
Pays : United States
Organisme : NHGRI NIH HHS
ID : U01 HG010971
Pays : United States
Organisme : NIDA NIH HHS
ID : U01 DA047638
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM123489
Pays : United States

Investigateurs

Haley J Abel (HJ)
Lucinda L Antonacci-Fulton (LL)
Mobin Asri (M)
Gunjan Baid (G)
Carl A Baker (CA)
Anastasiya Belyaeva (A)
Konstantinos Billis (K)
Guillaume Bourque (G)
Andrew Carroll (A)
Mark J P Chaisson (MJP)
Pi-Chuan Chang (PC)
Xian H Chang (XH)
Haoyu Cheng (H)
Justin Chu (J)
Sarah Cody (S)
Daniel E Cook (DE)
Robert M Cook-Deegan (RM)
Omar E Cornejo (OE)
Mark Diekhans (M)
Daniel Doerr (D)
Peter Ebert (P)
Jana Ebler (J)
Evan E Eichler (EE)
Jordan M Eizenga (JM)
Susan Fairley (S)
Olivier Fedrigo (O)
Adam L Felsenfeld (AL)
Xiaowen Feng (X)
Paul Flicek (P)
Giulio Formenti (G)
Adam Frankish (A)
Robert S Fulton (RS)
Yan Gao (Y)
Shilpa Garg (S)
Nanibaa' A Garrison (NA)
Carlos Garcia Giron (CG)
Richard E Green (RE)
Cristian Groza (C)
Leanne Haggerty (L)
Ira Hall (I)
William T Harvey (WT)
Marina Haukness (M)
David Haussler (D)
Simon Heumos (S)
Glenn Hickey (G)
Kendra Hoekzema (K)
Thibaut Hourlier (T)
Kerstin Howe (K)
Miten Jain (M)
Erich D Jarvis (ED)
Hanlee P Ji (HP)
Eimear E Kenny (EE)
Barbara A Koenig (BA)
Alexey Kolesnikov (A)
Jan O Korbel (JO)
Jennifer Kordosky (J)
HoJoon Lee (H)
Alexandra P Lewis (AP)
Heng Li (H)
Wen-Wei Liao (WW)
Shuangjia Lu (S)
Tsung-Yu Lu (TY)
Julian K Lucas (JK)
Hugo Magalhães (H)
Santiago Marco-Sola (S)
Pierre Marijon (P)
Charles Markello (C)
Tobias Marschall (T)
Fergal J Martin (FJ)
Ann McCartney (A)
Jennifer McDaniel (J)
Karen H Miga (KH)
Matthew W Mitchell (MW)
Jean Monlong (J)
Jacquelyn Mountcastle (J)
Katherine M Munson (KM)
Moses Njagi Mwaniki (MN)
Maria Nattestad (M)
Adam M Novak (AM)
Sergey Nurk (S)
Hugh E Olsen (HE)
Nathan D Olson (ND)
Benedict Paten (B)
Trevor Pesout (T)
Alice B Popejoy (AB)
David Porubsky (D)
Pjotr Prins (P)
Daniela Puiu (D)
Mikko Rautiainen (M)
Allison A Regier (AA)
Samuel Sacco (S)
Ashley D Sanders (AD)
Valerie A Schneider (VA)
Baergen I Schultz (BI)
Kishwar Shafin (K)
Jonas A Sibbesen (JA)
Jouni Sirén (J)
Michael W Smith (MW)
Heidi J Sofia (HJ)
Ahmad N Abou Tayoun (ANA)
Françoise Thibaud-Nissen (F)
Chad Tomlinson (C)
Francesca Floriana Tricomi (FF)
Flavia Villani (F)
Mitchell R Vollger (MR)
Justin Wagner (J)
Brian Walenz (B)
Ting Wang (T)
Jonathan M D Wood (JMD)
Aleksey V Zimin (AV)
Justin M Zook (JM)

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2023. The Author(s).

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Auteurs

Andrea Guarracino (A)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.
Genomics Research Centre, Human Technopole, Milan, Italy.
ORCID: 0000-0001-9744-131X

Silvia Buonaiuto (S)

Institute of Genetics and Biophysics, National Research Council, Naples, Italy.

Leonardo Gomes de Lima (LG)

Stowers Institute for Medical Research, Kansas City, MO, USA.
ORCID: 0000-0001-6340-6065

Tamara Potapova (T)

Stowers Institute for Medical Research, Kansas City, MO, USA.
ORCID: 0000-0003-2761-1795

Arang Rhie (A)

Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
ORCID: 0000-0002-9809-8127

Sergey Koren (S)

Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
ORCID: 0000-0002-1472-8962

Boris Rubinstein (B)

Stowers Institute for Medical Research, Kansas City, MO, USA.

Christian Fischer (C)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.

Jennifer L Gerton (JL)

Stowers Institute for Medical Research, Kansas City, MO, USA.
ORCID: 0000-0003-0743-3637

Adam M Phillippy (AM)

Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
ORCID: 0000-0003-2983-8934

Vincenza Colonna (V)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA.
Institute of Genetics and Biophysics, National Research Council, Naples, Italy.

Erik Garrison (E)

Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA. egarris5@uthsc.edu.
ORCID: 0000-0003-3821-631X

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Recombination between heterologous human...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Structures de chromosome › Centromère › Recombination between heterologous human...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Chromosomes › Chromosomes de mammifère › Chromosomes humains › Recombination between heterologous human...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › ADN ribosomique › Recombination between heterologous human...
questionsmedicales.fr › Phénomènes génétiques › Recombinaison génétique › Recombination between heterologous human...
questionsmedicales.fr › Phénomènes génétiques › Mutagenèse › Translocation génétique › Recombination between heterologous human...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Cytogénétique › Recombination between heterologous human...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Structures de chromosome › Télomère › Recombination between heterologous human...