Strategies for Surface Design in Surface Plasmon Resonance (SPR) Sensing.


Journal

Biosensors
ISSN: 2079-6374
Titre abrégé: Biosensors (Basel)
Pays: Switzerland
ID NLM: 101609191

Informations de publication

Date de publication:
07 Apr 2023
Historique:
received: 22 02 2023
revised: 31 03 2023
accepted: 05 04 2023
medline: 17 5 2023
pubmed: 15 5 2023
entrez: 15 5 2023
Statut: epublish

Résumé

Surface plasmon resonance (SPR) comprises several surface-sensitive techniques that enable the trace and ultra-trace detection of various analytes through affinity pairing. Although enabling label-free, sensitive detection and real-time monitoring, several issues remain to be addressed, such as poor stability, non-specific adsorption and the loss of operational activity of biomolecules. In this review, the progress over sensor modification, immobilization techniques and novel 2D nanomaterials, gold nanostructures and magnetic nanoparticles for signal amplification is discussed. The advantages and disadvantages of each design strategy will be provided together with some of the recent achievements.

Identifiants

pubmed: 37185540
pii: bios13040465
doi: 10.3390/bios13040465
pmc: PMC10136606
pii:
doi:

Substances chimiques

Gold 7440-57-5

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Romanian Ministry of Research, Innovation and Digitization
ID : project no PN-III-P4-ID-PCE2020-0998, within PNCDI III

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Auteurs

Cristina-Virginia Topor (CV)

Department of Analytical and Physical Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.
R&D Center LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.

Mihaela Puiu (M)

Department of Analytical and Physical Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.
R&D Center LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.

Camelia Bala (C)

Department of Analytical and Physical Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.
R&D Center LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania.

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Classifications MeSH