Ancestry of RNA/RNA interaction regions within segmented ribosomes.
nonstandard RNA interactions
segmented ribosomes
trypanosomatids
Journal
RNA (New York, N.Y.)
ISSN: 1469-9001
Titre abrégé: RNA
Pays: United States
ID NLM: 9509184
Informations de publication
Date de publication:
09 2023
09 2023
Historique:
received:
07
03
2023
accepted:
14
05
2023
pmc-release:
01
09
2024
medline:
18
8
2023
pubmed:
2
6
2023
entrez:
1
6
2023
Statut:
ppublish
Résumé
The ribosome is the universally conserved ribozyme that translates DNA coded instructions into proteins with the assistance of other RNA molecules, including transfer and messenger RNAs. Of particular interest is the segmentation phenomena, which is found in trypanosomatids and other protists. In these organisms, the large subunit ribosomal RNA is assembled from multiple smaller RNAs. This phenomenon posits several challenges to the folding and stabilization of such ribosomes to retain functionality and efficiency. In earlier studies, RNA/protein interactions were suggested to fully compensate for the fragmentation. Recently, several conserved RNA/RNA interaction regions were described in the cryo-EM structures of segmented ribosomes from trypanosomatids. These regions also seemed to aid in the folding and stabilization of such ribosomes, even before the ribosomal proteins start their association. In the present study, the existence of conserved RNA/RNA interaction regions shared between trypanosomatid and
Identifiants
pubmed: 37263782
pii: rna.079654.123
doi: 10.1261/rna.079654.123
pmc: PMC10573304
doi:
Substances chimiques
RNA
63231-63-0
RNA, Ribosomal
0
Ribosomal Proteins
0
RNA, Messenger
0
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
1388-1399Informations de copyright
© 2023 Rivas and Fox; Published by Cold Spring Harbor Laboratory Press for the RNA Society.
Références
Res Microbiol. 2006 Jan-Feb;157(1):57-68
pubmed: 16431085
Eukaryot Cell. 2014 Jun;13(6):727-37
pubmed: 24706018
Microbiol Mol Biol Rev. 2021 Dec 15;85(4):e0010421
pubmed: 34756086
PLoS One. 2015 Jun 29;10(6):e0131323
pubmed: 26121669
Mol Biol Evol. 2018 Aug 1;35(8):2065-2076
pubmed: 29788252
Nat Rev Microbiol. 2003 Nov;1(2):127-36
pubmed: 15035042
J Bacteriol. 2001 Oct;183(19):5782-7
pubmed: 11544246
Cell. 1981 Dec;27(3 Pt 2):487-96
pubmed: 6101203
Science. 2011 Dec 16;334(6062):1524-9
pubmed: 22096102
J Mol Evol. 2018 Jan;86(1):27-46
pubmed: 29189888
J Mol Biol. 1970 Apr 28;49(2):297-317
pubmed: 5447822
Cold Spring Harb Perspect Biol. 2012 May 01;4(5):
pubmed: 22550233
FEBS Lett. 1980 Oct 6;119(2):212-4
pubmed: 6159235
Mol Biochem Parasitol. 1983 Aug;8(4):297-304
pubmed: 6355842
Cell. 1983 Dec;35(3 Pt 2):849-57
pubmed: 6197186
Genome Res. 2003 Mar;13(3):407-12
pubmed: 12618371
Nucleic Acids Res. 2015 Dec 2;43(21):e142
pubmed: 26184874
Nat Rev Mol Cell Biol. 2008 Mar;9(3):242-53
pubmed: 18292779
Life (Basel). 2020 Sep 14;10(9):
pubmed: 32937913
Genome Biol Evol. 2020 Oct 1;12(10):1694-1710
pubmed: 32785681
J Mol Evol. 2006 Oct;63(4):513-25
pubmed: 17021929
Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10206-11
pubmed: 16014419
EMBO J. 1987 Apr;6(4):1063-71
pubmed: 16453755
Can J Biochem Cell Biol. 1983 Jan;61(1):38-45
pubmed: 6850409
Nucleic Acids Res. 2000 Jan 1;28(1):235-42
pubmed: 10592235
Mol Biochem Parasitol. 1980 Apr;1(2):91-6
pubmed: 7442711
Nature. 2013 Feb 21;494(7437):385-9
pubmed: 23395961
J Gen Microbiol. 1965 Jun;39(3):311-20
pubmed: 5324933
J Mol Biol. 1987 Jul 5;196(1):113-24
pubmed: 3656442
PLoS One. 2014 Feb 05;9(2):e88222
pubmed: 24505437
Cell. 2015 Jan 15;160(1-2):219-27
pubmed: 25594181
Science. 2011 May 20;332(6032):981-4
pubmed: 21596992
Cold Spring Harb Perspect Biol. 2010 Sep;2(9):a003483
pubmed: 20534711
Biochim Biophys Acta. 1998 Nov 26;1443(1-2):128-38
pubmed: 9838079
Nucleic Acids Res. 2022 Feb 28;50(4):1815-1828
pubmed: 35137169
RNA. 2022 Mar;28(3):340-352
pubmed: 34876487
RNA. 2023 Mar;29(3):263-272
pubmed: 36604112
Biol Chem. 2005 Sep;386(9):833-44
pubmed: 16164408
Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):373-8
pubmed: 15630082
Mol Cell Biol. 1981 Apr;1(4):347-57
pubmed: 6965102
Cell. 1978 May;14(1):169-78
pubmed: 667932
Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10268-73
pubmed: 8816789
Can J Biochem. 1979 Jun;57(6):914-26
pubmed: 476525
Angew Chem Int Ed Engl. 1999 Aug;38(16):2326-2343
pubmed: 10458781
J Mol Biol. 1990 Sep 5;215(1):85-91
pubmed: 2118961
Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):4899-903
pubmed: 11296253
Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12174-12179
pubmed: 27791004
Nucleic Acids Res. 2020 Nov 18;48(20):11750-11761
pubmed: 33091122
Science. 2000 Aug 11;289(5481):905-20
pubmed: 10937989
BMC Evol Biol. 2003 Jan 6;3:2
pubmed: 12515582
J Mol Biol. 1990 Sep 5;215(1):73-83
pubmed: 2118960
Nucleic Acids Res. 1986 Dec 9;14(23):9471-89
pubmed: 3797245
J Mol Biol. 2002 Jul 12;320(3):455-74
pubmed: 12096903
J Bacteriol. 1979 Sep;139(3):842-9
pubmed: 383696
Nat Commun. 2016 Oct 18;7:13223
pubmed: 27752045
J Mol Evol. 1999 Oct;49(4):413-23
pubmed: 10485999
Cell. 1983 Jun;33(2):320-2
pubmed: 6861202
RNA. 2001 Apr;7(4):499-512
pubmed: 11345429
Nucleic Acids Res. 1978 Feb;5(2):491-504
pubmed: 634795
J Mol Evol. 2022 Apr;90(2):166-175
pubmed: 35246710
J Gen Microbiol. 1976 Mar;93(1):82-8
pubmed: 944235
Trends Biochem Sci. 2003 Aug;28(8):411-8
pubmed: 12932729
Orig Life Evol Biosph. 2005 Dec;35(6):537-54
pubmed: 16254691
Science. 2000 Aug 11;289(5481):878-9
pubmed: 10960319