Structural analysis of a hormone-bound Striga strigolactone receptor.
Journal
Nature plants
ISSN: 2055-0278
Titre abrégé: Nat Plants
Pays: England
ID NLM: 101651677
Informations de publication
Date de publication:
06 2023
06 2023
Historique:
received:
19
09
2022
accepted:
25
04
2023
medline:
22
6
2023
pubmed:
2
6
2023
entrez:
1
6
2023
Statut:
ppublish
Résumé
Strigolactones (SLs) regulate many aspects of plant development, but ambiguities remain about how this hormone is perceived because SL-complexed receptor structures do not exist. We find that when SL binds the Striga receptor, ShHTL5, a series of conformational changes relative to the unbound state occur, but these events are not sufficient for signalling. Ligand-complexed receptors, however, form internal tunnels that posit an explanation for how SL exits its receptor after hydrolysis.
Identifiants
pubmed: 37264151
doi: 10.1038/s41477-023-01423-y
pii: 10.1038/s41477-023-01423-y
doi:
Substances chimiques
GR24 strigolactone
0
Lactones
0
Hormones
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
883-888Subventions
Organisme : Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada (NSERC Canadian Network for Research and Innovation in Machining Technology)
ID : 04298
Organisme : Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada (NSERC Canadian Network for Research and Innovation in Machining Technology)
ID : 06752
Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Nature Limited.
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