Iridium-Catalyzed Enantioselective Formal α-Allylic Alkylation of Acrylonitrile.

Allyl Compounds Iridium Acrylonitrile Stereoisomerism Catalysis Alkylation

Journal

Organic letters

ISSN: 1523-7052

Titre abrégé: Org Lett

Pays: United States

ID NLM: 100890393

Informations de publication

Date de publication:
23 Jun 2023

Historique:

medline: 26 6 2023

pubmed: 13 6 2023

entrez: 13 6 2023

Statut: ppublish

Résumé

A highly enantioselective formal α-allylic alkylation of acrylonitrile is developed using 4-cyano-3-oxotetrahydrothiophene (c-THT) as a safe and easy-to-handle surrogate of acrylonitrile. This two-step process consists of an Ir(I)/(

Identifiants

DOI: 10.1021/acs.orglett.3c01552 PMID: 37311003

pubmed: 37311003

doi: 10.1021/acs.orglett.3c01552

doi:

Substances chimiques

Allyl Compounds 0

Iridium 44448S9773

Acrylonitrile MP1U0D42PE

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

4520-4524

Iridium-Catalyzed Enantioselective Formal α-Allylic Alkylation of Acrylonitrile.

Journal

Informations de publication

Résumé

Identifiants

Substances chimiques

Types de publication

Langues

Sous-ensembles de citation

Pagination

Auteurs

Pankaj Roy (P)

Santanu Mukherjee (S)

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Classifications MeSH