A fluorescent probe for lipid droplet polarity imaging with low viscosity crosstalk.

Fluorescent Dyes / toxicity Lipid Droplets / metabolism Viscosity Hydrogen Peroxide / metabolism Fluorescence

Journal

The Analyst
ISSN: 1364-5528
Titre abrégé: Analyst
Pays: England
ID NLM: 0372652

Informations de publication

Date de publication:
10 Jul 2023
Historique:
medline: 12 7 2023
pubmed: 15 6 2023
entrez: 15 6 2023
Statut: epublish

Résumé

Monitoring the variations of lipid droplet (LD) polarity is of great significance for the investigation of LD-related cellular metabolism and function. We hereby report a lipophilic fluorescent probe (BTHO) with the feature of intramolecular charge transfer (ICT) for imaging the LD polarity in living cells. BTHO exhibits an obvious attenuation of fluorescence emission in response to the increase of environmental polarity. The linear response range of BTHO to polarity (

Identifiants

DOI: 10.1039/d3an00551h PMID: 37318022
pubmed: 37318022
doi: 10.1039/d3an00551h
doi:

Substances chimiques

Fluorescent Dyes 0
Hydrogen Peroxide BBX060AN9V

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3285-3294

Auteurs

Bo Lin (B)

Department of Chemistry, College of Sciences, Northeastern University, Shenyang, 110819, China. shuyang@mail.neu.edu.cn.
ORCID: 0009-0002-5815-4662

Zhenru Li (Z)

Department of Chemistry, College of Sciences, Northeastern University, Shenyang, 110819, China. shuyang@mail.neu.edu.cn.

Qi Zan (Q)

Institute of Environmental Science, Shanxi University, Taiyuan, 030006, China.

Li Fan (L)

Institute of Environmental Science, Shanxi University, Taiyuan, 030006, China.
ORCID: 0000-0002-4218-6638

Yang Shu (Y)

Department of Chemistry, College of Sciences, Northeastern University, Shenyang, 110819, China. shuyang@mail.neu.edu.cn.
ORCID: 0000-0002-1596-5943

Jianhua Wang (J)

Department of Chemistry, College of Sciences, Northeastern University, Shenyang, 110819, China. shuyang@mail.neu.edu.cn.
ORCID: 0000-0003-2175-3610

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › A fluorescent probe for lipid droplet polarity...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Gouttelettes lipidiques › A fluorescent probe for lipid droplet polarity...
questionsmedicales.fr › Phénomènes chimiques › Viscosité › A fluorescent probe for lipid droplet polarity...
questionsmedicales.fr › Composés chimiques organiques › Radicaux libres › Peroxydes › Peroxyde d'hydrogène › A fluorescent probe for lipid droplet polarity...
questionsmedicales.fr › Phénomènes physiques › Phénomènes optiques › Fluorescence › A fluorescent probe for lipid droplet polarity...