Palladium-Catalyzed Borylative Cyclization and Cyclopropanation of Terminal Alkyne-Derived Enynes.

Described herein is a palladium-catalyzed borylative cyclization and cyclopropanation of terminal alkyne-derived enynes, affording borylated bicycles, fused cycles, and bridged cycles in good isolated yields. The synthetic utility of this protocol was fully demonstrated by large scale reaction and synthetic derivatization of the borate group.