Detection & identification of hazardous narcotics and new psychoactive substances using Fourier transform infrared spectroscopy (FTIR).


Journal

Analytical methods : advancing methods and applications
ISSN: 1759-9679
Titre abrégé: Anal Methods
Pays: England
ID NLM: 101519733

Informations de publication

Date de publication:
06 07 2023
Historique:
medline: 10 7 2023
pubmed: 21 6 2023
entrez: 21 6 2023
Statut: epublish

Résumé

According to the latest World Drug Report, released by the United Nations Office on Drugs and Crime (UNODC), drug use is up 30% over the past decade and there are more drugs, and more types of drugs, than ever. Herein we use Fourier Transform Infrared Spectroscopy (FTIR) for the rapid ID of narcotics in a range of concentrations - from pure forms (as it is likely to be smuggled & transported) to street forms, often mixed with conventional cutting agents. Using FTIR, 75% of "street sample" narcotics were rapidly identified, and the effects of cutting agents on identification (ID) were also investigated. The limit of detection of MDMA was assessed, with a correct ID shown from 25% w/v. Concentration was correlated with Hit Quality Index, showing the capability of FTIR use in concentration estimation.

Identifiants

pubmed: 37341678
doi: 10.1039/d3ay00766a
doi:

Substances chimiques

Narcotics 0
Central Nervous System Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3225-3232

Auteurs

Samuel F Williams (SF)

Department of Infection, Immunity & Cardiovascular Disease, The University of Sheffield, Sheffield, UK. sfwilliams2@sheffield.ac.uk.

Robert Stokes (R)

Agilent Technologies, Sheffield, UK.

Pik Leung Tang (PL)

Agilent Technologies, Sheffield, UK.

Ana M Blanco-Rodriguez (AM)

Agilent Technologies, Sheffield, UK.

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Classifications MeSH