Amamine, an isoquinoline alkaloid from the Kitasatospora sp. HGTA304.


Journal

The Journal of antibiotics
ISSN: 1881-1469
Titre abrégé: J Antibiot (Tokyo)
Pays: England
ID NLM: 0151115

Informations de publication

Date de publication:
10 2023
Historique:
received: 27 02 2023
accepted: 18 06 2023
revised: 12 06 2023
medline: 23 10 2023
pubmed: 30 6 2023
entrez: 29 6 2023
Statut: ppublish

Résumé

Amamine (1), a new isoquinoline alkaloid, was isolated from the culture extract of an actinomycete Kitasatospora sp. HGTA304. The structure of 1 was determined by NMR and MS analyses in combination with UV data. Compound 1 displayed α-glucosidase inhibitory potential (IC

Identifiants

pubmed: 37386154
doi: 10.1038/s41429-023-00641-y
pii: 10.1038/s41429-023-00641-y
doi:

Substances chimiques

Glycoside Hydrolase Inhibitors 0
Alkaloids 0
Antineoplastic Agents 0
Isoquinolines 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

623-625

Informations de copyright

© 2023. The Author(s), under exclusive licence to the Japan Antibiotics Research Association.

Références

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Auteurs

Teppei Kawahara (T)

Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan. teppei@kumamoto-u.ac.jp.

Marin Ueda (M)

Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan.

Naoki Kishimoto (N)

Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan.

Tae Yasutake (T)

Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan.

Shogo Misumi (S)

Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan.

Hari Prasad Devkota (HP)

Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan.

Mikiyo Wada (M)

Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan.

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