A store-and-forward cloud-based telemonitoring system for automatic assessing dysarthria evolution in neurological diseases from video-recording analysis.

Deep learning Dysarthria Facial-landmark detection Store-and-forward telemonitoring

Journal

Computers in biology and medicine
ISSN: 1879-0534
Titre abrégé: Comput Biol Med
Pays: United States
ID NLM: 1250250

Informations de publication

Date de publication:
09 2023
Historique:
received: 21 03 2023
revised: 06 06 2023
accepted: 19 06 2023
medline: 21 8 2023
pubmed: 9 7 2023
entrez: 8 7 2023
Statut: ppublish

Résumé

Patients suffering from neurological diseases may develop dysarthria, a motor speech disorder affecting the execution of speech. Close and quantitative monitoring of dysarthria evolution is crucial for enabling clinicians to promptly implement patients' management strategies and maximizing effectiveness and efficiency of communication functions in term of restoring, compensating or adjusting. In the clinical assessment of orofacial structures and functions, at rest condition or during speech and non-speech movements, a qualitative evaluation is usually performed, throughout visual observation. To overcome limitations posed by qualitative assessments, this work presents a store-and-forward self-service telemonitoring system that integrates, within its cloud architecture, a convolutional neural network (CNN) for analyzing video recordings acquired by individuals with dysarthria. This architecture - called facial landmark Mask RCNN - aims at locating facial landmarks as a prior for assessing the orofacial functions related to speech and examining dysarthria evolution in neurological diseases. When tested on the Toronto NeuroFace dataset, a publicly available annotated dataset of video recordings from patients with amyotrophic lateral sclerosis (ALS) and stroke, the proposed CNN achieved a normalized mean error equal to 1.79 on localizing the facial landmarks. We also tested our system in a real-life scenario on 11 bulbar-onset ALS subjects, obtaining promising outcomes in terms of facial landmark position estimation. This preliminary study represents a relevant step towards the use of remote tools to support clinicians in monitoring the evolution of dysarthria.

Sections du résumé

BACKGROUND AND OBJECTIVES
Patients suffering from neurological diseases may develop dysarthria, a motor speech disorder affecting the execution of speech. Close and quantitative monitoring of dysarthria evolution is crucial for enabling clinicians to promptly implement patients' management strategies and maximizing effectiveness and efficiency of communication functions in term of restoring, compensating or adjusting. In the clinical assessment of orofacial structures and functions, at rest condition or during speech and non-speech movements, a qualitative evaluation is usually performed, throughout visual observation.
METHODS
To overcome limitations posed by qualitative assessments, this work presents a store-and-forward self-service telemonitoring system that integrates, within its cloud architecture, a convolutional neural network (CNN) for analyzing video recordings acquired by individuals with dysarthria. This architecture - called facial landmark Mask RCNN - aims at locating facial landmarks as a prior for assessing the orofacial functions related to speech and examining dysarthria evolution in neurological diseases.
RESULTS
When tested on the Toronto NeuroFace dataset, a publicly available annotated dataset of video recordings from patients with amyotrophic lateral sclerosis (ALS) and stroke, the proposed CNN achieved a normalized mean error equal to 1.79 on localizing the facial landmarks. We also tested our system in a real-life scenario on 11 bulbar-onset ALS subjects, obtaining promising outcomes in terms of facial landmark position estimation.
DISCUSSION AND CONCLUSIONS
This preliminary study represents a relevant step towards the use of remote tools to support clinicians in monitoring the evolution of dysarthria.

Identifiants

pubmed: 37421736
pii: S0010-4825(23)00659-5
doi: 10.1016/j.compbiomed.2023.107194
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

107194

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Lucia Migliorelli (L)

Department of Information Engineering, Univeristà Politecnica Delle Marche, Via Brecce Bianche 12, Ancona, 60121, Italy; AIDAPT S.r.l, Via Brecce Bianche 12, Ancona, 60121, Italy. Electronic address: l.migliorelli@univpm.it.

Daniele Berardini (D)

Department of Information Engineering, Univeristà Politecnica Delle Marche, Via Brecce Bianche 12, Ancona, 60121, Italy. Electronic address: d.berardini@pm.univpm.it.

Kevin Cela (K)

Department of Information Engineering, Univeristà Politecnica Delle Marche, Via Brecce Bianche 12, Ancona, 60121, Italy; AIDAPT S.r.l, Via Brecce Bianche 12, Ancona, 60121, Italy. Electronic address: kevin.cela@aidaptsrl.com.

Michela Coccia (M)

Centro Clinico NeuroMuscular Omnicentre (NeMO), Fondazione Serena Onlus, Via Conca 71, Torrette (Ancona), 60126, Italy. Electronic address: michela.coccia@centrocliniconemo.it.

Laura Villani (L)

Department of Neuroscience, Neurorehabilitation Clinic, Azienda Ospedaliero-Universitaria delle Marche, Via Conca 71, Torrette (Ancona), 60126, Italy. Electronic address: laura.villani@ospedaliriuniti.marche.it.

Emanuele Frontoni (E)

AIDAPT S.r.l, Via Brecce Bianche 12, Ancona, 60121, Italy; Department of Political Sciences, Communication, and International Relations, Università Degli Studi di Macerata, Via Giovanni Mario Crescimbeni 30, Macerata, 62100, Italy; NeMO Lab, Piazza dell'Ospedale Maggiore, Milano, 20162, Italy. Electronic address: emanuele.frontoni@unimc.it.

Sara Moccia (S)

The BioRobotics Institute, Department of Excellence in Robotics and AI, Scuola Superiore Sant'Anna, Piazza Martiri della Libertà, 33, Pisa, 56127, Italy. Electronic address: sara.moccia@santannapisa.it.

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