Clinical identification and microbiota analysis of
Chlamydia abortus
Chlamydia psittaci
Chlamydial pneumonia
Metagenomic next-generation sequencing
Pulmonary microbiome
Journal
Frontiers in cellular and infection microbiology
ISSN: 2235-2988
Titre abrégé: Front Cell Infect Microbiol
Pays: Switzerland
ID NLM: 101585359
Informations de publication
Date de publication:
2023
2023
Historique:
received:
02
02
2023
accepted:
29
05
2023
medline:
13
7
2023
pubmed:
12
7
2023
entrez:
12
7
2023
Statut:
epublish
Résumé
Recently, the incidence of chlamydial pneumonia caused by rare pathogens such as In the present study, we investigated both the pathogenic profile characteristics and the lower respiratory tract microbiota of pneumonia patients with different chlamydial infection patterns using mNGS. More co-infecting pathogens were found to be detectable in clinical samples from patients infected with The present study provides possible evidences supporting the close correlation between chlamydial infection, altered microbial diversity in patients' lungs and clinical parameters associated with infection or inflammation in patients, which also provides a new research direction to better understand the pathogenic mechanisms of pulmonary infections caused by
Identifiants
pubmed: 37434780
doi: 10.3389/fcimb.2023.1157540
pmc: PMC10331293
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1157540Informations de copyright
Copyright © 2023 Xie, Hu, Cao, Wu, Dai, Guo, Wang, Wei, Ren and Li.
Déclaration de conflit d'intérêts
Authors XC, WW, OW, LW and RR are employed by MatriDx Biotechnology Co., Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be constructed as a potential conflict of interest.
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