The bacterial cytochrome P450 (CYP) CYP125 enzymes can competitively oxidise sitosterol in the presence of cholesterol.

Sitosterols / metabolism Cytochrome P-450 Enzyme System / metabolism Cholesterol / metabolism Oxidation-Reduction Mycobacterium tuberculosis

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
27 Jul 2023
Historique:
medline: 28 7 2023
pubmed: 12 7 2023
entrez: 12 7 2023
Statut: epublish

Résumé

Cholesterol catabolism is an important survival mechanism for the pathogenic

Identifiants

DOI: 10.1039/d3cc02312e PMID: 37435674
pubmed: 37435674
doi: 10.1039/d3cc02312e
doi:

Substances chimiques

Sitosterols 0
Cytochrome P-450 Enzyme System 9035-51-2
Cholesterol 97C5T2UQ7J

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

9392-9395

Auteurs

Daniel Z Doherty (DZ)

Department of Chemistry, University of Adelaide, Adelaide, SA, 5005, Australia. daniel.z.doherty@adelaide.edu.au.
ORCID: 0000-0001-8522-7658

Amna Ghith (A)

Department of Chemistry, University of Adelaide, Adelaide, SA, 5005, Australia. daniel.z.doherty@adelaide.edu.au.
ORCID: 0000-0003-1753-6939

Ava Ho (A)

School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, 4067, Australia.

James J De Voss (JJ)

School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, 4067, Australia.
ORCID: 0000-0002-2659-5140

Stephen G Bell (SG)

Department of Chemistry, University of Adelaide, Adelaide, SA, 5005, Australia. daniel.z.doherty@adelaide.edu.au.
ORCID: 0000-0002-7457-9727

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Composés phytochimiques › Phytostérols › Sitostérol › The bacterial cytochrome P450 (CYP) CYP125...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Cytochromes › Cytochrome P-450 enzyme system › The bacterial cytochrome P450 (CYP) CYP125...
questionsmedicales.fr › Lipides › Lipides membranaires › Stérols › Cholestérol › The bacterial cytochrome P450 (CYP) CYP125...
questionsmedicales.fr › Métabolisme › Métabolisme énergétique › Oxydoréduction › The bacterial cytochrome P450 (CYP) CYP125...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets asporogènes à Gram positif › Bâtonnets asporogènes réguliers à Gram positif › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis › The bacterial cytochrome P450 (CYP) CYP125...