Shedding light on mitochondrial outer-membrane permeabilization and membrane potential: State of the art methods and biosensors.

Mitochondrial Membranes / metabolism Membrane Potentials Mitochondria / metabolism Apoptosis / physiology Biosensing Techniques
Biosensor MOMP Microscopy Mitochondrial membrane potential

Journal

Seminars in cell & developmental biology
ISSN: 1096-3634
Titre abrégé: Semin Cell Dev Biol
Pays: England
ID NLM: 9607332

Informations de publication

Date de publication:
15 Mar 2024
Historique:
received: 02 04 2023
revised: 21 06 2023
accepted: 04 07 2023
medline: 5 12 2023
pubmed: 13 7 2023
entrez: 12 7 2023
Statut: ppublish

Résumé

Membrane structural integrity is essential for optimal mitochondrial function. These organelles produce the energy needed for all vital processes, provided their outer and inner membranes are intact. This prevents the release of mitochondrial apoptogenic factors into the cytosol and ensures intact mitochondrial membrane potential (ΔΨ

Identifiants

DOI: 10.1016/j.semcdb.2023.07.003 PMID: 37438211
pubmed: 37438211
pii: S1084-9521(23)00141-6
doi: 10.1016/j.semcdb.2023.07.003
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

58-65

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that there is no conflict of interest.

Auteurs

Nikolay Popgeorgiev (N)

Cancer Cell Death laboratory, part of LabEX DEVweCAN, Cancer Initiation and Tumoral Cell Identity Department, CRCL, U1052 INSERM, UMR CNRS 5286, Centre Léon Bérard, Université Lyon I, Institut Convergence PLAsCAN Lyon, France; Institut Universitaire de France (IUF), Paris, France.

Clara Gil (C)

Cancer Cell Death laboratory, part of LabEX DEVweCAN, Cancer Initiation and Tumoral Cell Identity Department, CRCL, U1052 INSERM, UMR CNRS 5286, Centre Léon Bérard, Université Lyon I, Institut Convergence PLAsCAN Lyon, France.

Kevin Berthenet (K)

Cancer Cell Death laboratory, part of LabEX DEVweCAN, Cancer Initiation and Tumoral Cell Identity Department, CRCL, U1052 INSERM, UMR CNRS 5286, Centre Léon Bérard, Université Lyon I, Institut Convergence PLAsCAN Lyon, France.

Giulia Bertolin (G)

CNRS, Univ Rennes, IGDR (Institute of Genetics and Development of Rennes), Rennes, France. Electronic address: giulia.bertolin@univ-rennes.fr.

Gabriel Ichim (G)

Cancer Cell Death laboratory, part of LabEX DEVweCAN, Cancer Initiation and Tumoral Cell Identity Department, CRCL, U1052 INSERM, UMR CNRS 5286, Centre Léon Bérard, Université Lyon I, Institut Convergence PLAsCAN Lyon, France. Electronic address: gabriel.ichim@lyon.unicancer.fr.

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Classifications MeSH

questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Membranes intracellulaires › Membranes mitochondriales › Shedding light on mitochondrial outer-membrane...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Potentiels de membrane › Shedding light on mitochondrial outer-membrane...
questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Mitochondries › Shedding light on mitochondrial outer-membrane...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Apoptose › Shedding light on mitochondrial outer-membrane...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Techniques de biocapteur › Shedding light on mitochondrial outer-membrane...