Hydroxy Chalcones and Analogs with Chemopreventive Properties.
anti-inflammatory
antioxidants
chalcones
chemopreventive
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
26 Jun 2023
26 Jun 2023
Historique:
received:
20
05
2023
revised:
20
06
2023
accepted:
23
06
2023
medline:
17
7
2023
pubmed:
14
7
2023
entrez:
14
7
2023
Statut:
epublish
Résumé
The aim of this review is to highlight the chemopreventive properties of hydroxy-substituted natural and synthetic chalcones along with a number of their analogs. These products display various biological activities, and have many applications against various diseases. Antioxidant and anti-inflammatory properties of chalcones bearing hydroxy substituents are underlined. The influence of hydroxy substituents located on ring A, B, or both are systematized according to the exhibited biological properties.
Identifiants
pubmed: 37445844
pii: ijms241310667
doi: 10.3390/ijms241310667
pmc: PMC10341761
pii:
doi:
Substances chimiques
Chalcones
0
Antioxidants
0
Anti-Inflammatory Agents
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Med Chem. 2013 Nov;9(7):897-903
pubmed: 23305394
Phytother Res. 2002 Sep;16(6):539-44
pubmed: 12237811
Cancer Lett. 1995 Oct 20;97(1):33-7
pubmed: 7585475
Eur J Med Chem. 2015 Jun 15;98:69-114
pubmed: 26005917
Eur J Med Chem. 2014 Oct 6;85:758-77
pubmed: 25137491
Molecules. 2011 Feb 21;16(2):1749-60
pubmed: 21339710
Int Immunopharmacol. 2015 Mar;25(1):189-98
pubmed: 25614224
J Org Chem. 2022 Nov 4;87(21):14422-14432
pubmed: 36242558
Toxicology. 2005 Mar 1;208(1):81-93
pubmed: 15664435
Bioorg Chem. 2021 May;110:104773
pubmed: 33744807
Biochem Biophys Res Commun. 1998 Apr 17;245(2):435-8
pubmed: 9571170
Phytomedicine. 2009 Jan;16(1):85-94
pubmed: 19022639
Int J Mol Sci. 2014 Oct 14;15(10):18525-39
pubmed: 25318055
J Med Chem. 2009 Nov 26;52(22):7228-35
pubmed: 19883086
Biol Pharm Bull. 2007 Aug;30(8):1450-5
pubmed: 17666802
Curr Med Chem. 2005;12(4):481-99
pubmed: 15720256
Bioorg Med Chem Lett. 2018 Sep 15;28(17):2969-2975
pubmed: 30017320
Arch Pharm Res. 2007 Nov;30(11):1359-67
pubmed: 18087801
Curr Clin Pharmacol. 2010 Feb;5(1):1-29
pubmed: 19891604
Bioorg Chem. 2020 Jan;95:103530
pubmed: 31887477
J Pharm Pharmacol. 2000 Feb;52(2):163-71
pubmed: 10714946
Biomolecules. 2021 Aug 13;11(8):
pubmed: 34439870
J Biol Chem. 2002 Jan 11;277(2):1361-9
pubmed: 11698411
Bioorg Med Chem. 2009 Dec 1;17(23):8073-85
pubmed: 19853459
Biol Pharm Bull. 2009 May;32(5):941-4
pubmed: 19420769
Curr Med Chem. 1999 Dec;6(12):1125-49
pubmed: 10519918
Z Naturforsch C J Biosci. 2008 May-Jun;63(5-6):361-5
pubmed: 18669021
Exp Mol Med. 2012 Jun 30;44(6):369-77
pubmed: 22382990
Phytochemistry. 2004 May;65(10):1317-30
pubmed: 15231405
Molecules. 2021 May 08;26(9):
pubmed: 34066803
Int J Mol Sci. 2016 Feb 22;17(2):260
pubmed: 26907262
Bioorg Med Chem Lett. 2009 Jul 1;19(13):3607-10
pubmed: 19447618
Eur J Med Chem. 2000 Apr;35(4):449-57
pubmed: 10858605
Eur J Med Chem. 2015 Aug 28;101:496-524
pubmed: 26188621
Int J Mol Sci. 2021 Aug 29;22(17):
pubmed: 34502286
Pharmaceuticals (Basel). 2022 Oct 11;15(10):
pubmed: 36297362
Molecules. 2020 Feb 05;25(3):
pubmed: 32033283
Bioorg Chem. 2021 Mar;108:104681
pubmed: 33571811
J Phys Chem A. 2007 Feb 15;111(6):1138-45
pubmed: 17253666
Fitoterapia. 2020 Oct;146:104717
pubmed: 32877711
Genes Nutr. 2011 May;6(2):125-47
pubmed: 21484163
J Med Chem. 2011 Dec 8;54(23):8110-23
pubmed: 21988173
Med Chem (Los Angeles). 2015 Aug;5(8):388-404
pubmed: 26798565
J Med Chem. 2013 Aug 8;56(15):6136-45
pubmed: 23859213
Bioorg Chem. 2022 May;122:105662
pubmed: 35276602
PLoS One. 2013 Jul 05;8(7):e68566
pubmed: 23861918
Med Chem Res. 2015 Apr;24(4):1672-1680
pubmed: 25866456
Chem Pharm Bull (Tokyo). 2004 Nov;52(11):1326-9
pubmed: 15516755
Nat Prod Rep. 2004 Aug;21(4):539-73
pubmed: 15282635
Curr Issues Mol Biol. 2022 Oct 26;44(11):5209-5220
pubmed: 36354666
J Enzyme Inhib Med Chem. 2015 Jun;30(3):484-91
pubmed: 25198887
J Med Chem. 1995 Jul 7;38(14):2794-7
pubmed: 7629818
Arch Pharm Res. 2008 Sep;31(9):1145-52
pubmed: 18806957
Bioorg Chem. 2019 Jun;87:335-365
pubmed: 30921740
Molecules. 2008 Aug 28;13(8):1923-30
pubmed: 18794793
ACS Omega. 2022 Aug 02;7(32):27769-27786
pubmed: 35990442
Molecules. 2020 Jun 24;25(12):
pubmed: 32599797
J Biol Chem. 2014 Dec 26;289(52):35839-48
pubmed: 25368326
Planta Med. 2001 Mar;67(2):108-13
pubmed: 11301853
Antibiotics (Basel). 2020 Sep 04;9(9):
pubmed: 32899705
Molecules. 2017 Nov 01;22(11):
pubmed: 29104222
Plants (Basel). 2020 Jun 20;9(6):
pubmed: 32575698
Chem Biol Interact. 2019 Jan 25;298:72-79
pubmed: 30408460
Biochim Biophys Acta. 2001 Dec 17;1550(2):144-52
pubmed: 11755203
BMC Vet Res. 2014 Dec 31;10:961
pubmed: 25551777
Bioorg Chem. 2021 Mar;108:104689
pubmed: 33571810
Life Sci. 2016 Mar 1;148:154-72
pubmed: 26876916
Med Chem. 2022;18(1):88-96
pubmed: 33380306
RSC Adv. 2020 Oct 12;10(61):37463-37472
pubmed: 35521233
Nutrition. 2016 Nov-Dec;32(11-12):1171-8
pubmed: 27238957
Chem Biol Interact. 2023 Jan 5;369:110297
pubmed: 36496109
Curr Med Chem. 2015;22(30):3407-25
pubmed: 26219392
Bioorg Med Chem. 2010 Oct 1;18(19):6987-94
pubmed: 20813535
Eur J Pharmacol. 2016 Mar 5;774:135-43
pubmed: 26852953
Front Pharmacol. 2021 Jan 18;11:592654
pubmed: 33536909
J Nat Med. 2008 Apr;62(2):188-94
pubmed: 18404321
Adv Exp Med Biol. 1995;369:167-74
pubmed: 7598004
Angew Chem Int Ed Engl. 2000 Apr;39(7):1253-1256
pubmed: 10767022
Chem Rev. 2017 Jun 28;117(12):7762-7810
pubmed: 28488435
Molecules. 2021 Nov 26;26(23):
pubmed: 34885754
Nat Prod Rep. 2010 Jun;27(6):809-38
pubmed: 20358127
Chem Pharm Bull (Tokyo). 2008 Jul;56(7):897-901
pubmed: 18591798
Planta Med. 2007 May;73(5):496-8
pubmed: 17566151
Eur J Med Chem. 2017 Jun 16;133:121-138
pubmed: 28384544