Medicines postpartum in Sweden and coverage in Janusmed Breastfeeding.
Breast feeding milk
Clinical database management systems
Human cohort studies decision support systems
Janusmed breastfeeding
Medicines
Postpartum
Journal
European journal of clinical pharmacology
ISSN: 1432-1041
Titre abrégé: Eur J Clin Pharmacol
Pays: Germany
ID NLM: 1256165
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
12
10
2022
accepted:
15
06
2023
medline:
17
8
2023
pubmed:
15
7
2023
entrez:
15
7
2023
Statut:
ppublish
Résumé
The purpose of this article is (1) to investigate which medicines are prescribed and dispensed to women the first 6 months postpartum, (2) to identify medicines dispensed postpartum but not recommended during breastfeeding, and (3) to find medicines commonly dispensed postpartum, but not currently included in Janusmed Breastfeeding. In this register-based cohort study covering births between January 2017 and August 2019, the Swedish Medical Birth Register (MBR), the Prescribed Drug Register, and Janusmed Breastfeeding were linked to identify medicines dispensed to women during the first 6 months postpartum, and how they are covered and classified in Janusmed Breastfeeding. During the first 6 months postpartum, 66% of women purchased at least one prescription medicine from the pharmacy. The most common medicines were contraceptive agents, analgesics, antibiotics, and glucocorticoids. A third of the 30 most commonly dispensed medicines have no information available about the safety of use in breastfeeding. The most dispensed medicines, where the database advises against use in breastfeeding, included several antitussive agents, a local anaesthetic, and several gestagens. The most commonly dispensed medicines not covered by the Janusmed Breastfeeding were medicines for dry eyes, for assisted reproduction, and HIV. Prescribed medicines compatible with breastfeeding are more common during the first 6 months postpartum than medicines not compatible with breastfeeding, but medicines which lack evidence for safety in breastfeeding are still commonly used.
Identifiants
pubmed: 37452835
doi: 10.1007/s00228-023-03528-x
pii: 10.1007/s00228-023-03528-x
pmc: PMC10427528
doi:
Substances chimiques
Progestins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1261-1269Informations de copyright
© 2023. The Author(s).
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