Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT

Serotonin / metabolism Receptor, Serotonin, 5-HT2A / metabolism Receptor, Serotonin, 5-HT2C / metabolism Brain / metabolism

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
27 07 2023
Historique:
medline: 28 7 2023
pubmed: 18 7 2023
entrez: 18 7 2023
Statut: ppublish

Résumé

The serotonin 5-HT

Identifiants

DOI: 10.1021/acs.jmedchem.3c00908 PMID: 37462530
pubmed: 37462530
doi: 10.1021/acs.jmedchem.3c00908
doi:

Substances chimiques

Serotonin 333DO1RDJY
oleylamide 7L25QK8BWO
Receptor, Serotonin, 5-HT2A 0
Receptor, Serotonin, 5-HT2C 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9992-10009

Subventions

Organisme : NIMH NIH HHS
ID : R21 MH093844
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA038446
Pays : United States
Organisme : NIDA NIH HHS
ID : K05 DA020087
Pays : United States
Organisme : NIDA NIH HHS
ID : P30 DA028821
Pays : United States
Organisme : NIDA NIH HHS
ID : F31 DA038922
Pays : United States
Organisme : NIDA NIH HHS
ID : F31 DA045511
Pays : United States
Organisme : NIMH NIH HHS
ID : HHSN271201300017C
Pays : United States
Organisme : NIDA NIH HHS
ID : T32 DA007287
Pays : United States

Auteurs

Jianping Chen (J)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
Chemical Biology Program and Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Erik J Garcia (EJ)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
ORCID: 0000-0003-4760-7048

Christina R Merritt (CR)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Joshua C Zamora (JC)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Andrew A Bolinger (AA)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
Chemical Biology Program and Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Konrad Pazdrak (K)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Susan J Stafford (SJ)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Randy C Mifflin (RC)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Eric A Wold (EA)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
Chemical Biology Program and Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Christopher T Wild (CT)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
Chemical Biology Program and Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Haiying Chen (H)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
Chemical Biology Program and Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Noelle C Anastasio (NC)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
Chemical Biology Program and Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
ORCID: 0000-0001-5579-4213

Kathryn A Cunningham (KA)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
Chemical Biology Program and Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
ORCID: 0000-0002-4257-1739

Jia Zhou (J)

Center for Addiction Sciences and Therapeutics, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
Chemical Biology Program and Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.
ORCID: 0000-0002-2811-1090

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › Autacoïdes › Sérotonine › Discovery of Novel Oleamide Analogues as...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs sérotoninergiques › Récepteurs de la sérotonine de type 5-HT2 › Récepteur de la sérotonine de type 5-HT2A › Discovery of Novel Oleamide Analogues as...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs sérotoninergiques › Récepteurs de la sérotonine de type 5-HT2 › Récepteur de la sérotonine de type 5-HT2C › Discovery of Novel Oleamide Analogues as...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Discovery of Novel Oleamide Analogues as...