Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter.

Potassium Channels / chemistry Binding Sites Chloroquinolinols / chemistry Membrane Potentials

Journal

Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179

Informations de publication

Date de publication:
18 07 2023
Historique:
received: 04 01 2023
accepted: 07 07 2023
medline: 21 7 2023
pubmed: 19 7 2023
entrez: 18 7 2023
Statut: epublish

Résumé

The TWIK-related spinal cord K

Identifiants

DOI: 10.1038/s42003-023-05114-4 PMID: 37464013 PMC: PMC10354012
pubmed: 37464013
doi: 10.1038/s42003-023-05114-4
pii: 10.1038/s42003-023-05114-4
pmc: PMC10354012
doi:

Substances chimiques

Potassium Channels 0
cloxyquin BPF36H1G6S
Chloroquinolinols 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

745

Informations de copyright

© 2023. The Author(s).

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Auteurs

Julian Alexander Schreiber (JA)

Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany. j.schreiber@uni-muenster.de.
Westfälische Wilhelms-Universität Münster, Institut für Pharmazeutische und Medizinische Chemie, Corrensstr. 48, Münster, Germany. j.schreiber@uni-muenster.de.
ORCID: 0000-0002-3847-7539

Anastasia Derksen (A)

Westfälische Wilhelms-Universität Münster, Institut für Pharmazeutische und Medizinische Chemie, Corrensstr. 48, Münster, Germany.

Gunnar Goerges (G)

Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany.

Sven Schütte (S)

Institute of Physiology and Pathophysiology, Vegetative Physiology, Philipps-University Marburg, Marburg, Germany.

Jasmin Sörgel (J)

Westfälische Wilhelms-Universität Münster, Institut für Pharmazeutische und Medizinische Chemie, Corrensstr. 48, Münster, Germany.

Aytug K Kiper (AK)

Institute of Physiology and Pathophysiology, Vegetative Physiology, Philipps-University Marburg, Marburg, Germany.
ORCID: 0000-0003-2850-2523

Nathalie Strutz-Seebohm (N)

Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany.

Tobias Ruck (T)

Department of Neurology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
ORCID: 0000-0001-6332-8650

Sven G Meuth (SG)

Department of Neurology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.

Niels Decher (N)

Institute of Physiology and Pathophysiology, Vegetative Physiology, Philipps-University Marburg, Marburg, Germany.
ORCID: 0000-0002-9433-687X

Guiscard Seebohm (G)

Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany.
Westfälische Wilhelms-Universität Münster, GRK 2515, Chemical biology of ion channels (Chembion), Münster, Germany.
ORCID: 0000-0001-9303-5373

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › Cloxyquin activates hTRESK by allosteric...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Sites de fixation › Cloxyquin activates hTRESK by allosteric...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Hydroxyquinoléines › Hydroxy-8 quinoléine › Chloroquinoléinols › Cloxyquin activates hTRESK by allosteric...
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