Application of instantaneous nebulization dispersive liquid-phase microextraction combined with HPLC for the determination of chalcone and isoflavone in traditional Chinese medicines.
chalcone
dispersive liquid-phase microextraction
isoflavone
nebulization
nozzle
Journal
Journal of separation science
ISSN: 1615-9314
Titre abrégé: J Sep Sci
Pays: Germany
ID NLM: 101088554
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
revised:
10
07
2023
received:
08
05
2023
accepted:
13
07
2023
medline:
23
10
2023
pubmed:
24
7
2023
entrez:
24
7
2023
Statut:
ppublish
Résumé
A simple and rapid instantaneous nebulization dispersive liquid-phase microextraction method was developed, and combined with high-performance liquid chromatography for determination of the contents of seven analytes in traditional Chinese medicines. In this study, using the sprinkler device to achieve instantaneous synchronous dispersion and extraction, only one spray can rapidly achieve the concentration and enrichment of seven kinds of chalcone and isoflavones. The key factors affecting the extraction efficiency were optimized including the type and volume of extractant, the pH and salt concentration of the sample phase, and the number of dispersion. Under the optimal conditions, the enrichment factor of the target analytes ranged from 103.1 to 180.9, with good linearity and correlation coefficients above 0.9970. The limits of detection ranged from 0.02 to 0.15 ng/mL, with good accuracy (recoveries 91.1 to 108.9%) and precision (relative standard deviations 1.5-7.1%). This method has short extraction time (2 s), low organic solvent consumption and high enrichment effect, so it has a wide application prospects.
Identifiants
pubmed: 37485627
doi: 10.1002/jssc.202300326
doi:
Substances chimiques
Chalcones
0
Chalcone
5S5A2Q39HX
Isoflavones
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2300326Subventions
Organisme : Nature Science Foundation of Shanxi Province
ID : 201901D111207
Organisme : National Natural Science Foundation of China
ID : 81973287
Informations de copyright
© 2023 Wiley-VCH GmbH.
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