Epigenetic Age Acceleration in Frontotemporal Lobar Degeneration: A Comprehensive Analysis in the Blood and Brain.
DNA methylation aging
epigenetic clock
frontotemporal dementia
frontotemporal lobar degeneration
progressive supranuclear palsy
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
24 07 2023
24 07 2023
Historique:
received:
18
05
2023
revised:
22
06
2023
accepted:
17
07
2023
medline:
31
7
2023
pubmed:
29
7
2023
entrez:
29
7
2023
Statut:
epublish
Résumé
Frontotemporal lobar degeneration (FTLD) includes a heterogeneous group of disorders pathologically characterized by the degeneration of the frontal and temporal lobes. In addition to major genetic contributors of FTLD such as mutations in
Identifiants
pubmed: 37508584
pii: cells12141922
doi: 10.3390/cells12141922
pmc: PMC10378390
pii:
doi:
Substances chimiques
OTUD4 protein, human
EC 3.4.19.12
Ubiquitin-Specific Proteases
EC 3.4.19.12
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Medical Research Council
ID : MR/M008924/1
Pays : United Kingdom
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