Occurrence of L1M Elements in Chromosomal Rearrangements Associated to Chronic Myeloid Leukemia (CML): Insights from Patient-Specific Breakpoints Characterization.


Journal

Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097

Informations de publication

Date de publication:
27 06 2023
Historique:
received: 01 06 2023
revised: 19 06 2023
accepted: 22 06 2023
medline: 31 7 2023
pubmed: 29 7 2023
entrez: 29 7 2023
Statut: epublish

Résumé

Chronic myeloid leukemia (CML) is a rare myeloproliferative disorder caused by the reciprocal translocation t(9;22)(q34;q11) in hematopoietic stem cells (HSCs). This chromosomal translocation results in the formation of an extra-short chromosome 22, called a Philadelphia chromosome (Ph), containing the

Identifiants

pubmed: 37510256
pii: genes14071351
doi: 10.3390/genes14071351
pmc: PMC10379433
pii:
doi:

Substances chimiques

Fusion Proteins, bcr-abl EC 2.7.10.2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

Bioinformatics. 2012 Sep 15;28(18):i333-i339
pubmed: 22962449
PLoS One. 2012;7(9):e44196
pubmed: 23028501
Curr Cancer Drug Targets. 2015;15(3):227-42
pubmed: 25808076
Nat Genet. 2020 Mar;52(3):306-319
pubmed: 32024998
Cell Cycle. 2015;14(23):3659-60
pubmed: 25714683
Cancer Biomark. 2017 Dec 12;21(1):41-53
pubmed: 29036785
Science. 2003 Apr 18;300(5618):455
pubmed: 12702868
Nat Biotechnol. 2011 Jan;29(1):24-6
pubmed: 21221095
Genome Res. 2004 Nov;14(11):2245-52
pubmed: 15520288
Oncogene. 1992 Dec;7(12):2519-23
pubmed: 1461655
Oncogene. 2010 Apr 29;29(17):2509-16
pubmed: 20101201
Eur J Haematol. 2021 Oct;107(4):436-448
pubmed: 34139044
Bioinformatics. 2009 Jul 15;25(14):1754-60
pubmed: 19451168
BMC Genomics. 2016 Jun 14;17:463
pubmed: 27301971
Nucleic Acids Res. 2015 Jan;43(Database issue):D805-11
pubmed: 25355519
J Mol Diagn. 2009 Sep;11(5):482-7
pubmed: 19710400
Oncogene. 2002 Aug 12;21(35):5400-13
pubmed: 12154403
J Exp Med. 1996 Mar 1;183(3):811-20
pubmed: 8642285
BMC Cancer. 2014 Jun 03;14:396
pubmed: 24893616
Cell Death Dis. 2018 Mar 2;9(3):349
pubmed: 29500381
Leukemia. 2013 Oct;27(10):2105-7
pubmed: 23588714
Leuk Res. 2008 Mar;32(3):487-90
pubmed: 17765966
Genes Chromosomes Cancer. 2002 Oct;35(2):97-112
pubmed: 12203773
Gene. 2022 Jan 15;808:145975
pubmed: 34592349
Oncotarget. 2019 Apr 12;10(28):2738-2754
pubmed: 31105873
Oncoscience. 2014 Jul 23;1(7):510-21
pubmed: 25594053
PLoS One. 2019 Jul 18;14(7):e0218444
pubmed: 31318870
Am J Hematol. 2018 Jul;93(7):E162-E164
pubmed: 29633310
Bioinformatics. 2018 Sep 15;34(18):3094-3100
pubmed: 29750242
Nat Rev Genet. 2001 Mar;2(3):196-206
pubmed: 11256071
Nature. 1960 Dec 31;188:1165-6
pubmed: 13685929
Bioinformatics. 2010 Mar 15;26(6):841-2
pubmed: 20110278
Baillieres Clin Haematol. 1997 Jun;10(2):203-22
pubmed: 9376660
Genes Chromosomes Cancer. 2008 Jul;47(7):625-32
pubmed: 18398823
Hum Mol Genet. 1998 May;7(5):767-76
pubmed: 9536079

Auteurs

Alberto L'Abbate (A)

Institute of Biomembranes, Bioenergetics, and Molecular Biotechnologies, National Research Council (IBIOM-CNR), 70125 Bari, Italy.

Vittoria Moretti (V)

Genomic Medicine Research Center, Department of Medicine and Surgery, University of Insubria, Via JH Dunant 5 Varese, 21100 Varese, Italy.

Ester Pungolino (E)

Division of Hematology, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.

Giovanni Micheloni (G)

Genomic Medicine Research Center, Department of Medicine and Surgery, University of Insubria, Via JH Dunant 5 Varese, 21100 Varese, Italy.

Roberto Valli (R)

Genomic Medicine Research Center, Department of Medicine and Surgery, University of Insubria, Via JH Dunant 5 Varese, 21100 Varese, Italy.

Annalisa Frattini (A)

Genetics and Biomedical Research Institute, National Research Council (IRGB-CNR), 20090 Milano, Italy.

Matteo Barcella (M)

Department of Health Science, University degli Studi of Milan, Via Rudini 8, 20142 Milan, Italy.

Francesco Acquati (F)

Department of Biotechnology and Life Science, University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.
Genomic Medicine Research Center, Department of Biotechnology and Life Science, University of Insubria, Via JH Dunant 3, 21100 Varese, Italy.

Rolland A Reinbold (RA)

Institute of Biomedical Technologies, National Research Council of Italy, 20054 Segrate, Milano, Italy.

Lucy Costantino (L)

Department of Molecular Genetics, Centro Diagnostico Italiano, 20147 Milano, Italy.

Fulvio Ferrara (F)

Department of Molecular Genetics, Centro Diagnostico Italiano, 20147 Milano, Italy.

Alessandra Trojani (A)

Division of Hematology, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.

Mario Ventura (M)

Department of Biology, University of Bari 'Aldo Moro', Via Edoardo Orabona 4, 70124 Bari, Italy.

Giovanni Porta (G)

Genomic Medicine Research Center, Department of Medicine and Surgery, University of Insubria, Via JH Dunant 5 Varese, 21100 Varese, Italy.

Roberto Cairoli (R)

Division of Hematology, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH