Central role of Tim17 in mitochondrial presequence protein translocation.

Mitochondria / metabolism Mitochondrial Membranes / metabolism Mitochondrial Precursor Protein Import Complex Proteins / metabolism Protein Transport Saccharomyces cerevisiae / cytology Saccharomyces cerevisiae Proteins / metabolism

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
Sep 2023
Historique:
received: 12 10 2022
accepted: 25 07 2023
medline: 22 9 2023
pubmed: 2 8 2023
entrez: 1 8 2023
Statut: ppublish

Résumé

The presequence translocase of the mitochondrial inner membrane (TIM23) represents the major route for the import of nuclear-encoded proteins into mitochondria

Identifiants

DOI: 10.1038/s41586-023-06477-8 PMID: 37527780 PMC: PMC10511324
pubmed: 37527780
doi: 10.1038/s41586-023-06477-8
pii: 10.1038/s41586-023-06477-8
pmc: PMC10511324
doi:

Substances chimiques

Mitochondrial Precursor Protein Import Complex Proteins 0
Saccharomyces cerevisiae Proteins 0
TIM17 protein, S cerevisiae 0
TIM23 protein, S cerevisiae 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

627-634

Informations de copyright

© 2023. The Author(s).

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Auteurs

Laura F Fielden (LF)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Jakob D Busch (JD)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
ORCID: 0000-0002-6317-5188

Sandra G Merkt (SG)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Faculty of Biology, University of Freiburg, Freiburg, Germany.

Iniyan Ganesan (I)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
ORCID: 0000-0002-1082-202X

Conny Steiert (C)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Hanna B Hasselblatt (HB)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
ORCID: 0009-0009-4905-6113

Jon V Busto (JV)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Christophe Wirth (C)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
ORCID: 0000-0001-8864-6508

Nicole Zufall (N)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Sibylle Jungbluth (S)

Medical Biochemistry and Molecular Biology, Center for Molecular Signaling, PZMS, Saarland University, Homburg, Germany.

Katja Noll (K)

Medical Biochemistry and Molecular Biology, Center for Molecular Signaling, PZMS, Saarland University, Homburg, Germany.

Julia M Dung (JM)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Ludmila Butenko (L)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Karina von der Malsburg (K)

Medical Biochemistry and Molecular Biology, Center for Molecular Signaling, PZMS, Saarland University, Homburg, Germany.

Hans-Georg Koch (HG)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
ORCID: 0000-0001-5913-0334

Carola Hunte (C)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
CIBSS-Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.
BIOSS-Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany.
ORCID: 0000-0002-0826-3986

Martin van der Laan (M)

Medical Biochemistry and Molecular Biology, Center for Molecular Signaling, PZMS, Saarland University, Homburg, Germany. martin.van-der-laan@uks.eu.
ORCID: 0000-0003-0789-9912

Nils Wiedemann (N)

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany. nils.wiedemann@biochemie.uni-freiburg.de.
CIBSS-Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany. nils.wiedemann@biochemie.uni-freiburg.de.
BIOSS-Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany. nils.wiedemann@biochemie.uni-freiburg.de.
ORCID: 0000-0001-8305-6728

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Classifications MeSH

questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Mitochondries › Central role of Tim17 in mitochondrial...
questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Membranes intracellulaires › Membranes mitochondriales › Central role of Tim17 in mitochondrial...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines mitochondriales › Protéines de transport de la membrane mitochondriale › Protéines du complexe d'import des protéines précurseurs mitochondriales › Central role of Tim17 in mitochondrial...
questionsmedicales.fr › Métabolisme › Transport biologique › Transport des protéines › Central role of Tim17 in mitochondrial...
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Saccharomyces › Saccharomyces cerevisiae › Central role of Tim17 in mitochondrial...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines fongiques › Protéines de Saccharomyces cerevisiae › Central role of Tim17 in mitochondrial...