Association between N-Terminal Pyrenes Stabilizes the Collagen Triple Helix.

Peptides / chemistry Collagen / chemistry Pyrenes Circular Dichroism Protein Conformation

Journal

The Journal of organic chemistry
ISSN: 1520-6904
Titre abrégé: J Org Chem
Pays: United States
ID NLM: 2985193R

Informations de publication

Date de publication:
18 08 2023
Historique:
medline: 21 8 2023
pubmed: 2 8 2023
entrez: 2 8 2023
Statut: ppublish

Résumé

Collagen model peptides featuring the fluorophore pyrene at their N-termini have been synthesized, and their thermal denaturation has been examined using circular dichroism (CD) and fluorescence spectroscopies. Flanking the (Pro-Hyp-Gly)

Identifiants

DOI: 10.1021/acs.joc.3c01175 PMID: 37531574
pubmed: 37531574
doi: 10.1021/acs.joc.3c01175
doi:

Substances chimiques

Peptides 0
Collagen 9007-34-5
Pyrenes 0

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

11885-11894

Auteurs

Jared M Keever (JM)

Department of Chemistry, Science and Technology Building, East Carolina University, Greenville, North Carolina 27858-4353, United States.

Patrick D Banzon (PD)

Department of Chemistry, Science and Technology Building, East Carolina University, Greenville, North Carolina 27858-4353, United States.

Megan K Hales (MK)

Department of Chemistry, Science and Technology Building, East Carolina University, Greenville, North Carolina 27858-4353, United States.

Andrew L Sargent (AL)

Department of Chemistry, Science and Technology Building, East Carolina University, Greenville, North Carolina 27858-4353, United States.
ORCID: 0000-0002-5758-8787

William E Allen (WE)

Department of Chemistry, Science and Technology Building, East Carolina University, Greenville, North Carolina 27858-4353, United States.
ORCID: 0000-0003-0650-9441

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Association between N-Terminal Pyrenes...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Collagène › Association between N-Terminal Pyrenes...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Pyrènes › Association between N-Terminal Pyrenes...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Dichroïsme circulaire › Association between N-Terminal Pyrenes...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Association between N-Terminal Pyrenes...