Factors Associated with the Transition Time to Full Enteral Feeding in Newborns with Hypoxic Ischemic Encephalopathy.


Journal

Archives of Iranian medicine
ISSN: 1735-3947
Titre abrégé: Arch Iran Med
Pays: Iran
ID NLM: 100889644

Informations de publication

Date de publication:
01 08 2022
Historique:
received: 16 04 2021
accepted: 20 08 2021
medline: 7 8 2023
pubmed: 6 8 2023
entrez: 6 8 2023
Statut: epublish

Résumé

We aimed to assess the factors associated with the transition time to full enteral feeding (FEF) in newborns with hypoxic ischemic encephalopathy (HIE) undergoing therapeutic hypothermia. We obtained data retrospectively from medical records of the neonates diagnosed with HIE and treated by therapeutic hypothermia to evaluate the factors associated with transition time to FEF. Sixty-one neonates were included in the study. The median gestational age (GA) and birth weight were 39 (37-40) weeks and 3245 (2715-3575) grams, respectively. APGAR scores at the first and fifth minutes were 3 (1-5) and 6 (4-7), respectively. Fifty-seven (93.4%) of the newborns were diagnosed as having moderate HIE, and 4 (6.6%) of them had severe HIE. Transition time to FEF was found to be negatively correlated with gestational week ( Clinicians should be more careful while starting to feed babies undergoing therapeutic hypothermia with higher lactate levels and impaired renal functions, and should be encouraged to feed clinically stable neonates with HIE as soon as possible, as the transition time to FEF could be related with better clinical outcomes.

Sections du résumé

BACKGROUND
We aimed to assess the factors associated with the transition time to full enteral feeding (FEF) in newborns with hypoxic ischemic encephalopathy (HIE) undergoing therapeutic hypothermia.
METHODS
We obtained data retrospectively from medical records of the neonates diagnosed with HIE and treated by therapeutic hypothermia to evaluate the factors associated with transition time to FEF.
RESULTS
Sixty-one neonates were included in the study. The median gestational age (GA) and birth weight were 39 (37-40) weeks and 3245 (2715-3575) grams, respectively. APGAR scores at the first and fifth minutes were 3 (1-5) and 6 (4-7), respectively. Fifty-seven (93.4%) of the newborns were diagnosed as having moderate HIE, and 4 (6.6%) of them had severe HIE. Transition time to FEF was found to be negatively correlated with gestational week (
CONCLUSION
Clinicians should be more careful while starting to feed babies undergoing therapeutic hypothermia with higher lactate levels and impaired renal functions, and should be encouraged to feed clinically stable neonates with HIE as soon as possible, as the transition time to FEF could be related with better clinical outcomes.

Identifiants

pubmed: 37543877
doi: 10.34172/aim.2022.87
doi:

Substances chimiques

Lactic Acid 33X04XA5AT

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

547-551

Informations de copyright

© 2022 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Auteurs

Asli Okbay Gunes (AO)

University of Health Sciences, Zeynep Kamil Maternity and Children's Training and Research Hospital -Istanbul, Turkey.

Nilgun Karadag (N)

University of Health Sciences, Zeynep Kamil Maternity and Children's Training and Research Hospital -Istanbul, Turkey.

Sevilay Topcuoglu (S)

University of Health Sciences, Zeynep Kamil Maternity and Children's Training and Research Hospital -Istanbul, Turkey.

Elif Ozalkaya (E)

University of Health Sciences, Zeynep Kamil Maternity and Children's Training and Research Hospital -Istanbul, Turkey.

Handan Hakyemez Toptan (HH)

University of Health Sciences, Zeynep Kamil Maternity and Children's Training and Research Hospital -Istanbul, Turkey.

Emre Dincer (E)

University of Health Sciences, Zeynep Kamil Maternity and Children's Training and Research Hospital -Istanbul, Turkey.

Hakan Cakir (H)

University of Health Sciences, Zeynep Kamil Maternity and Children's Training and Research Hospital -Istanbul, Turkey.

Guner Karatekin (G)

University of Health Sciences, Zeynep Kamil Maternity and Children's Training and Research Hospital -Istanbul, Turkey.

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