Bone on-a-chip: a 3D dendritic network in a screening platform for osteocyte-targeted drugs.

Osteocytes Bone and Bones Collagen / chemistry Hydrogels Lab-On-A-Chip Devices
3D models drug screening hydroxyapatite nanoparticles microfluidics osteocytes osteoporosis

Journal

Biofabrication
ISSN: 1758-5090
Titre abrégé: Biofabrication
Pays: England
ID NLM: 101521964

Informations de publication

Date de publication:
01 09 2023
Historique:
received: 13 01 2023
accepted: 08 08 2023
medline: 4 9 2023
pubmed: 9 8 2023
entrez: 8 8 2023
Statut: epublish

Résumé

Age-related musculoskeletal disorders, including osteoporosis, are frequent and associated with long lasting morbidity, in turn significantly impacting on healthcare system sustainability. There is therefore a compelling need to develop reliable preclinical models of disease and drug screening to validate novel drugs possibly on a personalized basis, without the need of

Identifiants

DOI: 10.1088/1758-5090/acee23 PMID: 37552982
pubmed: 37552982
doi: 10.1088/1758-5090/acee23
doi:

Substances chimiques

Collagen 9007-34-5
Hydrogels 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Creative Commons Attribution license.

Auteurs

Maria Veronica Lipreri (MV)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.

Gemma Di Pompo (G)

Biomedical Science, Technologies, and Nanobiotecnologiy Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Elisa Boanini (E)

Department of Chemistry 'Giacomo Ciamician', University of Bologna, Bologna, Italy.
ORCID: 0000-0003-3754-0273

Gabriela Graziani (G)

Biomedical Science, Technologies, and Nanobiotecnologiy Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Enrico Sassoni (E)

Department of Civil, Chemical, Environmental and Materials Engineering, University of Bologna, Bologna, Italy.

Nicola Baldini (N)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Biomedical Science, Technologies, and Nanobiotecnologiy Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Sofia Avnet (S)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
ORCID: 0000-0002-7843-0591

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Classifications MeSH

questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Ostéoblastes › Ostéocytes › Bone on-a-chip: a 3D dendritic network in a...
questionsmedicales.fr › Tissus › Tissu conjonctif › Os et tissu osseux › Bone on-a-chip: a 3D dendritic network in a...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Collagène › Bone on-a-chip: a 3D dendritic network in a...
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › Bone on-a-chip: a 3D dendritic network in a...
questionsmedicales.fr › Équipement et fournitures › Équipement et fournitures électriques › Laboratoires sur puces › Bone on-a-chip: a 3D dendritic network in a...