Genomic dissection of endemic carbapenem resistance reveals metallo-beta-lactamase dissemination through clonal, plasmid and integron transfer.

Integrons / genetics beta-Lactamases / genetics Bacterial Proteins / genetics Plasmids / genetics Serratia marcescens / genetics Carbapenems / pharmacology Genomics Microbial Sensitivity Tests Anti-Bacterial Agents / pharmacology

Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
08 08 2023
Historique:
received: 29 03 2023
accepted: 03 07 2023
medline: 10 8 2023
pubmed: 9 8 2023
entrez: 8 8 2023
Statut: epublish

Résumé

Infections caused by metallo-beta-lactamase-producing organisms (MBLs) are a global health threat. Our understanding of transmission dynamics and how MBLs establish endemicity remains limited. We analysed two decades of bla

Identifiants

DOI: 10.1038/s41467-023-39915-2 PMID: 37553339 PMC: PMC10409761
pubmed: 37553339
doi: 10.1038/s41467-023-39915-2
pii: 10.1038/s41467-023-39915-2
pmc: PMC10409761
doi:

Substances chimiques

beta-Lactamases EC 3.5.2.6
Bacterial Proteins 0
Carbapenems 0
Anti-Bacterial Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4764

Informations de copyright

© 2023. Springer Nature Limited.

Références

Clin Infect Dis. 2021 Dec 6;73(11):e3912-e3920
pubmed: 32663248
Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):25043-25054
pubmed: 32968015
Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1135-1140
pubmed: 28096418
Antimicrob Agents Chemother. 2008 Aug;52(8):2984-7
pubmed: 18490506
PLoS Comput Biol. 2017 Jun 8;13(6):e1005595
pubmed: 28594827
Front Microbiol. 2019 Jan 31;10:44
pubmed: 30766518
PLoS Comput Biol. 2023 Mar 2;19(3):e1010905
pubmed: 36862631
Microb Genom. 2021 May;7(5):
pubmed: 33961543
PLoS One. 2014 Nov 19;9(11):e112963
pubmed: 25409509
Bioinformatics. 2019 Nov 15;:
pubmed: 31730192
J Infect Dis. 2017 Feb 15;215(suppl_1):S28-S36
pubmed: 28375512
Genome Med. 2022 Aug 23;14(1):97
pubmed: 35999578
Nat Microbiol. 2021 May;6(5):606-616
pubmed: 33782584
Microb Genom. 2020 Jul;6(7):
pubmed: 32553019
Genome Med. 2014 Nov 20;6(11):90
pubmed: 25422674
Clin Infect Dis. 2019 Nov 13;69(Suppl 7):S521-S528
pubmed: 31724045
Nat Commun. 2018 Nov 30;9(1):5114
pubmed: 30504855
PLoS One. 2010 Jun 25;5(6):e11147
pubmed: 20593022
Nat Commun. 2023 Aug 8;14(1):4764
pubmed: 37553339
Nucleic Acids Res. 2017 Jul 3;45(W1):W30-W35
pubmed: 28472413
Bioinformatics. 2014 Aug 1;30(15):2114-20
pubmed: 24695404
Med J Aust. 2013 Mar 18;198(5):267-9
pubmed: 23496403
Microb Genom. 2016 Apr 29;2(4):e000056
pubmed: 28348851
Elife. 2020 Apr 14;9:
pubmed: 32285801
Nat Biotechnol. 2019 May;37(5):540-546
pubmed: 30936562
Antimicrob Agents Chemother. 2020 Apr 21;64(5):
pubmed: 32094139
Infect Control Hosp Epidemiol. 2007 Jan;28(1):98-101
pubmed: 17230397
Clin Microbiol Infect. 2021 Dec;27(12):1856.e7-1856.e13
pubmed: 33915285
BMC Bioinformatics. 2021 Jul 31;22(1):390
pubmed: 34332528
Microb Genom. 2020 Jan;6(1):
pubmed: 31860437
Nat Commun. 2020 Jan 24;11(1):466
pubmed: 31980604
Antimicrob Agents Chemother. 2012 Nov;56(11):6029-32
pubmed: 22926566
Nucleic Acids Res. 2016 Jul 8;44(W1):W16-21
pubmed: 27141966
Clin Microbiol Rev. 2018 Aug 1;31(4):
pubmed: 30068738
Mol Biol Evol. 2020 May 1;37(5):1530-1534
pubmed: 32011700
J Comput Biol. 2012 May;19(5):455-77
pubmed: 22506599
Microb Genom. 2020 Oct;6(10):
pubmed: 32969786
PLoS Comput Biol. 2022 Jan 24;18(1):e1009802
pubmed: 35073327
J Clin Microbiol. 2020 Aug 24;58(9):
pubmed: 32554477
mBio. 2018 Feb 6;9(1):
pubmed: 29437920
Bioinformatics. 2013 Apr 15;29(8):1072-5
pubmed: 23422339
Antimicrob Agents Chemother. 2018 Apr 26;62(5):
pubmed: 29483121
Microb Genom. 2021 Sep;7(9):
pubmed: 34559044
J Antimicrob Chemother. 2004 Sep;54(3):699-700
pubmed: 15282242
PLoS Comput Biol. 2020 Jun 26;16(6):e1007981
pubmed: 32589667
Antimicrob Agents Chemother. 2006 Jan;50(1):399-400
pubmed: 16377723
Nat Methods. 2017 Jun;14(6):587-589
pubmed: 28481363
Clin Infect Dis. 2005 Dec 1;41(11):1549-56
pubmed: 16267725
JAMA Netw Open. 2019 Feb 1;2(2):e187660
pubmed: 30768186
J Open Source Softw. 2019 Dec 10;4(44):
pubmed: 35978566
Genome Biol. 2016 Jun 20;17(1):132
pubmed: 27323842
mBio. 2019 Sep 3;10(5):
pubmed: 31481386
Bioinformatics. 2014 Jul 15;30(14):2068-9
pubmed: 24642063
Nucleic Acids Res. 2004 Mar 19;32(5):1792-7
pubmed: 15034147
Front Microbiol. 2021 Feb 18;12:614058
pubmed: 33679638
Bioinformatics. 2011 Apr 1;27(7):1009-10
pubmed: 21278367
Nucleic Acids Res. 2015 Feb 18;43(3):e15
pubmed: 25414349
J Antimicrob Chemother. 2020 Apr 1;75(4):873-882
pubmed: 31960024

Auteurs

Nenad Macesic (N)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.
Centre to Impact AMR, Monash University, Clayton, Australia.

Jane Hawkey (J)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.
ORCID: 0000-0001-9661-5293

Ben Vezina (B)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.

Jessica A Wisniewski (JA)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.
ORCID: 0000-0002-9923-6579

Hugh Cottingham (H)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.

Luke V Blakeway (LV)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.

Taylor Harshegyi (T)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.
ORCID: 0000-0001-9620-8735

Katherine Pragastis (K)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.

Gnei Zweena Badoordeen (GZ)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.

Amanda Dennison (A)

Microbiology Unit, Alfred Hospital, Melbourne, Australia.

Denis W Spelman (DW)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.
Microbiology Unit, Alfred Hospital, Melbourne, Australia.

Adam W J Jenney (AWJ)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia.
Microbiology Unit, Alfred Hospital, Melbourne, Australia.

Anton Y Peleg (AY)

Department of Infectious Diseases, The Alfred Hospital and Central Clinical School, Monash University, Melbourne, Australia. anton.peleg@monash.edu.
Centre to Impact AMR, Monash University, Clayton, Australia. anton.peleg@monash.edu.
Infection Program, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia. anton.peleg@monash.edu.
ORCID: 0000-0002-2296-2126

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Intégrons › Genomic dissection of endemic carbapenem...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Amidohydrolases › bêta-Lactamases › Genomic dissection of endemic carbapenem...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Genomic dissection of endemic carbapenem...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Plasmides › Genomic dissection of endemic carbapenem...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Serratia › Serratia marcescens › Genomic dissection of endemic carbapenem...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › bêta-Lactames › Carbapénèmes › Genomic dissection of endemic carbapenem...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génomique › Genomic dissection of endemic carbapenem...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Genomic dissection of endemic carbapenem...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Genomic dissection of endemic carbapenem...