Prophylactic antibiotics has no benefit for outcome in clean myringoplasty-A register-based cohort study from SwedEar.
Humans
Anti-Bacterial Agents
/ administration & dosage
Antibiotic Prophylaxis
/ statistics & numerical data
Cohort Studies
Myringoplasty
/ adverse effects
Registries
/ statistics & numerical data
Retrospective Studies
Sweden
/ epidemiology
Treatment Outcome
Tympanic Membrane Perforation
/ drug therapy
Tympanic Membrane
/ drug effects
Follow-Up Studies
Surgical Wound Infection
/ epidemiology
Wound Healing
/ drug effects
myringoplasty
postoperative infection
prophylactic antibiotics
tympanic membrane
tympanoplasty
Journal
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
ISSN: 1749-4486
Titre abrégé: Clin Otolaryngol
Pays: England
ID NLM: 101247023
Informations de publication
Date de publication:
11 2023
11 2023
Historique:
revised:
10
07
2023
received:
13
12
2022
accepted:
15
07
2023
medline:
12
10
2023
pubmed:
9
8
2023
entrez:
9
8
2023
Statut:
ppublish
Résumé
To investigate if prophylactic antibiotics (PA) in conjunction with myringoplasty of clean and uninfected ears entails a reduction of postoperative infections within 6 weeks after surgery, and whether it affects the healing rate of the tympanic membrane (TM) at follow-up, 6-24 months after surgery. A retrospective cohort study of prospectively collected data. Data extracted from The Swedish Quality Register for Ear Surgery (SwedEar), the years 2013-2019. All patients in SwedEar with a registered clean conventional myringoplasty (tympanoplasty type I) including a follow-up visit. The effect of PA use on TM healing rate at follow-up and postoperative infection within 6 weeks of surgery. In the study group (n = 1665) 86.2% had a healed TM at follow-up. There was no significant difference between the groups that had PA administered (87.2%) or not (86.1%). A total of 8.0% had a postoperative infection within 6 weeks. Postoperative infection occurred in 10.2% of the group that received PA (n = 187) compared with 7.7% of the group that did not receive PA. However, this difference was not statistically significant. Postoperative infection within 6 weeks significantly lowered the frequency of healed TMs. PA administered during clean conventional myringoplasty does not improve the chance of having a healed TM at follow up, nor decrease the risk of having a postoperative infection within 6 weeks after surgery.
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
895-901Subventions
Organisme : County Council Västernorrland
Informations de copyright
© 2023 The Authors. Clinical Otolaryngology published by John Wiley & Sons Ltd.
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