Imaging techniques for studying solid dosage formulation: Principles and applications.

Chemistry, Pharmaceutical / methods Tablets Solubility Drug Liberation Kinetics Dosage Forms
Disintegration Dissolution Imaging technology Solid dosage forms Visualization

Journal

Journal of controlled release : official journal of the Controlled Release Society
ISSN: 1873-4995
Titre abrégé: J Control Release
Pays: Netherlands
ID NLM: 8607908

Informations de publication

Date de publication:
09 2023
Historique:
received: 08 07 2023
revised: 04 08 2023
accepted: 08 08 2023
medline: 11 9 2023
pubmed: 12 8 2023
entrez: 11 8 2023
Statut: ppublish

Résumé

Classic methods for evaluating the disintegration and dissolution kinetics of solid dosage forms are no longer sufficient to meet the growing demands in the pharmaceutical field. Hence, scientists have turned to imaging techniques and computer technology to develop innovative visualization methods. These methods allow for a visual understanding of the disintegration or dissolution process and offer valuable insights into the drug release kinetics. This article aims to provide an overview of the commonly used imaging techniques and their applications in studying the disintegration or dissolution of solid dosage forms. Therefore, imaging presents a novel and alternative approach to understanding the mechanisms of disintegration and dissolution in the formulation study of solid dosages.

Identifiants

DOI: 10.1016/j.jconrel.2023.08.013 PMID: 37567508
pubmed: 37567508
pii: S0168-3659(23)00511-4
doi: 10.1016/j.jconrel.2023.08.013
pii:
doi:

Substances chimiques

Tablets 0
Dosage Forms 0

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

659-670

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors have no conflicts of interest to declare.

Auteurs

Jiajia Gengji (J)

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.

Tao Gong (T)

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.

Zhirong Zhang (Z)

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.

Li Deng (L)

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.. Electronic address: denglisunny@163.com.

Yao Fu (Y)

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.. Electronic address: yfu4@scu.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Chimie pharmaceutique › Imaging techniques for studying solid dosage...
questionsmedicales.fr › Préparations pharmaceutiques › Comprimés › Imaging techniques for studying solid dosage...
questionsmedicales.fr › Phénomènes chimiques › Solubilité › Imaging techniques for studying solid dosage...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Pharmacocinétique › Libération de médicament › Imaging techniques for studying solid dosage...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Cinétique › Imaging techniques for studying solid dosage...
questionsmedicales.fr › Techniques d'investigation › Formes posologiques › Imaging techniques for studying solid dosage...