Personalized CFTR Modulator Therapy for
CFTR
CFTR modulator
G85E
N1303K
cystic fibrosis
human nasal epithelial cells
intestinal current measurement
nasal potential difference
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
02 Aug 2023
02 Aug 2023
Historique:
received:
21
06
2023
revised:
28
07
2023
accepted:
31
07
2023
medline:
14
8
2023
pubmed:
12
8
2023
entrez:
12
8
2023
Statut:
epublish
Résumé
CFTR modulator therapy with elexacaftor/tezacaftor/ivacaftor (ETI) has been approved for people with CF and at least one F508del allele in Europe. In the US, the ETI label has been expanded to 177 rare
Identifiants
pubmed: 37569738
pii: ijms241512365
doi: 10.3390/ijms241512365
pmc: PMC10418744
pii:
doi:
Substances chimiques
Cystic Fibrosis Transmembrane Conductance Regulator
126880-72-6
Chlorides
0
Benzodioxoles
0
CFTR protein, human
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Christiane Herzog Stiftung, Stuttgart, Germany and the Mukoviszidose Institut gGmbH, Bonn
ID : 2101 C-H-P
Organisme : Federal Ministry of Education and Research
ID : 82DZL009B1
Organisme : Deutsche Forschungsgemeinschaft
ID : CRC 1449 - project 431232613; sub-project Z02; and project 450557679
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