Oxidative stress and activation of H2A.X in lung alveolar epithelial cells (A549) by nanoparticulate carbon black.


Journal

Respiratory physiology & neurobiology
ISSN: 1878-1519
Titre abrégé: Respir Physiol Neurobiol
Pays: Netherlands
ID NLM: 101140022

Informations de publication

Date de publication:
10 2023
Historique:
received: 19 05 2023
revised: 06 08 2023
accepted: 13 08 2023
medline: 6 9 2023
pubmed: 17 8 2023
entrez: 16 8 2023
Statut: ppublish

Résumé

Fine airborne particulate matter enter the respiratory system, induce oxidative stress and initiate DNA damage. The aim of our study was the estimation of cell viability, oxidative stress, DNA damage, cell cycle alterations and activation of histone H2A.X. Experiments were done on lung alveolar epithelial (A549) cells grown for 24 h with 200 µg mL

Identifiants

pubmed: 37586603
pii: S1569-9048(23)00128-3
doi: 10.1016/j.resp.2023.104140
pii:
doi:

Substances chimiques

Histones 0
Soot 0
RNA, Messenger 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

104140

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.

Auteurs

A Niechoda (A)

Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland.

J Roslan (J)

Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland.

K Maciorowska (K)

Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland.

M Rosłan (M)

Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland.

K Ejsmont (K)

Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland.

A Holownia (A)

Department of Pharmacology, Medical University of Bialystok, Mickiewicza 2c, Bialystok 15-222, Poland. Electronic address: adam.holownia@umb.edu.pl.

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Classifications MeSH