Childhood mortality and associated factors in Migori County, Kenya: evidence from a cross-sectional survey.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
22 08 2023
Historique:
medline: 24 8 2023
pubmed: 23 8 2023
entrez: 22 8 2023
Statut: epublish

Résumé

The under-five mortality (U5M) rate in Kenya (41 per 1000 live births) remains significantly above international goals (25 per 1000 live births). This is further exacerbated by regional inequalities in mortality. We aimed to describe U5M in Migori County, Kenya, and identify associated factors that can serve as programming targets. Cross-sectional observational survey. Areas served by the Lwala Community Alliance and control areas in Migori County, Kenya. This study included 15 199 children born to respondents during the 18 years preceding the survey. The primary outcome was mortality in the first 5 years of life. The survey was powered to detect a 10% change in various health metrics over time with 80% power. A total of 15 199 children were included in the primary analyses, and 230 (1.5%) were deceased before the fifth birthday. The U5M rate from 2016 to 2021 was 32.2 per 1000 live births. Factors associated with U5M included year of birth (HR 0.926, p<0.001), female sex (HR 0.702, p=0.01), parental marriage (HR 0.642, p=0.036), multiple gestation pregnancy (HR 2.776, p<0.001), birth spacing less than 18 months (HR 1.894, p=0.005), indoor smoke exposure (HR 1.916, p=0.027) and previous familial contribution to the National Hospital Insurance Fund (HR 0.553, p=0.009). The most common cause of death was malaria. We describe factors associated with childhood mortality in a Kenyan community using survival analyses of complete birth histories. Mortality rates will serve as the baseline for future programme evaluation as a part of a 10-year study design. This provides both the hyperlocal information needed to improve programming and generalisable conclusions for other organisations working in similar environments.

Identifiants

pubmed: 37607788
pii: bmjopen-2023-074056
doi: 10.1136/bmjopen-2023-074056
pmc: PMC10445361
doi:

Substances chimiques

HR 916 0

Types de publication

Journal Article Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e074056

Informations de copyright

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

Lancet. 2011 Nov 12;378(9804):1717-26
pubmed: 22078686
BMC Public Health. 2014 Mar 20;14:266
pubmed: 24649944
Am J Trop Med Hyg. 2005 Dec;73(6):1151-8
pubmed: 16354829
BMC Public Health. 2013;13 Suppl 3:S8
pubmed: 24564764
J Biomed Inform. 2019 Jul;95:103208
pubmed: 31078660
Lancet. 2016 Oct 8;388(10053):1725-1774
pubmed: 27733285
PLoS One. 2018 Jul 2;13(7):e0199786
pubmed: 29965975
PLoS One. 2018 Oct 25;13(10):e0205977
pubmed: 30359408
BMC Pediatr. 2022 Jun 13;22(1):341
pubmed: 35698091
J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
PLoS One. 2021 Nov 16;16(11):e0259848
pubmed: 34784390
Biomed Res Int. 2022 Dec 5;2022:1181409
pubmed: 36518629
Pediatr Blood Cancer. 2014 May;61(5):913-8
pubmed: 24347434
Glob Health Action. 2014 Oct 29;7:25581
pubmed: 25377340
PLoS One. 2021 Aug 25;16(8):e0256555
pubmed: 34432837
Glob Health Action. 2014 Feb 11;7:23137
pubmed: 24560256
Am J Perinatol. 2014 Feb;31(2):125-32
pubmed: 23512321
J Biosoc Sci. 2013 Nov;45(6):779-98
pubmed: 22958417
BMC Public Health. 2020 Jan 20;20(1):87
pubmed: 31959153
J Biosoc Sci. 1995 Oct;27(4):393-404
pubmed: 7593046
Stud Fam Plann. 2012 Jun;43(2):93-114
pubmed: 23175949
Int J Epidemiol. 2006 Jun;35(3):751-5
pubmed: 16481364
AIDS. 2022 Jan 1;36(1):59-68
pubmed: 34586084
Pan Afr Med J. 2022 Feb 08;41:108
pubmed: 35432704
Afr J Reprod Health. 2021 Feb;25(1):29-40
pubmed: 34077108
Stud Fam Plann. 2013 Mar;44(1):45-66
pubmed: 23512873
BMC Public Health. 2017 Jan 10;17(1):53
pubmed: 28068969
BMC Health Serv Res. 2017 Jul 3;17(1):454
pubmed: 28673344
BMC Public Health. 2015 Mar 19;15:268
pubmed: 25884813
Glob Health Action. 2015 Nov 09;8:29724
pubmed: 26562139
Bull World Health Organ. 2004 Apr;82(4):265-73
pubmed: 15259255
World Health Stat Q. 1991;44(3):107-14
pubmed: 1949878
J Interpers Violence. 2022 Mar;37(5-6):2083-2101
pubmed: 32627662
BMJ Open. 2015 Mar 27;5(3):e006779
pubmed: 25818271
Emerg Themes Epidemiol. 2007 Jun 01;4:8
pubmed: 17543102
PLoS One. 2018 Sep 7;13(9):e0203690
pubmed: 30192880
Bull World Health Organ. 2003;81(2):140-5
pubmed: 12756980
J Glob Health. 2018 Jun;8(1):010404
pubmed: 29423189
BMJ Glob Health. 2022 Nov;7(11):
pubmed: 36375850
Biom J. 2009 Feb;51(1):110-22
pubmed: 19197959
BMJ Glob Health. 2021 Aug;6(8):
pubmed: 34452940

Auteurs

Joseph R Starnes (JR)

Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA joseph.starnes@vumc.org.
Lwala Community Alliance, Rongo, Kenya.

Ash Rogers (A)

Lwala Community Alliance, Rongo, Kenya.

Jane Wamae (J)

Lwala Community Alliance, Rongo, Kenya.

Vincent Okoth (V)

Lwala Community Alliance, Rongo, Kenya.

Sandra A Mudhune (SA)

Lwala Community Alliance, Rongo, Kenya.

Alyn Omondi (A)

Adaptive Model for Research and Empowerment of Communities in Africa, Kisumu, Kenya.

Vincent Were (V)

Kenya Medical Research Institute, Nairobi, Kenya.

Doreen Baraza Awino (D)

Lwala Community Alliance, Rongo, Kenya.

Christina Hope Lefebvre (CH)

Department of Cultures, Societies, and Global Studies, Northeastern University, Boston, Massachusetts, USA.

Samantha Yap (S)

Department of Cultures, Societies, and Global Studies, Northeastern University, Boston, Massachusetts, USA.

Tom Otieno Odhong (T)

Department of Health Services, Migori County Government, Migori, Kenya.

Beffy Vill (B)

Department of Health Services, Migori County Government, Migori, Kenya.

Lawrence Were (L)

Department of Global Health, Boston University, Boston, Massachusetts, USA.

Richard Wamai (R)

Department of Cultures, Societies, and Global Studies, Northeastern University, Boston, Massachusetts, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH