Are physicians ready for precision antibiotic prescribing? A qualitative analysis of the acceptance of artificial intelligence-enabled clinical decision support systems in India and Singapore.

Antibiotic prescribing Antimicrobial resistance Artificial intelligence Clinical decision support system

Journal

Journal of global antimicrobial resistance
ISSN: 2213-7173
Titre abrégé: J Glob Antimicrob Resist
Pays: Netherlands
ID NLM: 101622459

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 06 04 2023
revised: 16 05 2023
accepted: 18 08 2023
medline: 4 12 2023
pubmed: 29 8 2023
entrez: 28 8 2023
Statut: ppublish

Résumé

Artificial intelligence (AI)-driven clinical decision support systems (CDSSs) can augment antibiotic decision-making capabilities, but physicians' hesitancy in adopting them may undermine their utility. We conducted a cross-country comparison of physician perceptions on the barriers and facilitators in accepting an AI-enabled CDSS for antibiotic prescribing. We conducted in-depth interviews with physicians from the National Centre for Infectious Diseases (NCID), Singapore, and Christian Medical College Vellore (CMCV), India, between April and December 2022. Our semi-structured in-depth interview guides were anchored on Venkatesh's UTAUT model. We used clinical vignettes to illustrate the application of AI in clinical decision support for antibiotic prescribing and explore medico-legal concerns. Most NCID physicians felt that an AI-enabled CDSS could facilitate antibiotic prescribing, while most CMCV physicians were sceptical about the tool's utility. The hesitancy in adopting an AI-enabled CDSS stems from concerns about the lack of validated and successful examples, fear of losing autonomy and clinical skills, difficulty of use, and impediment in work efficiency. Physicians from both sites felt that a user-friendly interface, integration with workflow, transparency of output, a guiding medico-legal framework, and training and technical support would improve the uptake of an AI-enabled CDSS. In conclusion, the acceptance of AI-enabled CDSSs depends on the physician's confidence with the tool's recommendations, perceived ease of use, familiarity with AI, the organisation's digital culture and support, and the presence of medico-legal governance of AI. Progressive implementation and continuous feedback are essential to allay scepticism around the utility of AI-enabled CDSSs.

Identifiants

pubmed: 37640155
pii: S2213-7165(23)00140-6
doi: 10.1016/j.jgar.2023.08.016
pmc: PMC10684720
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

76-85

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.

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Auteurs

Zhilian Huang (Z)

Infectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, Singapore.

Mithun Mohan George (MM)

Department of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.

Yi-Roe Tan (YR)

International Digital Health & AI Research Collaborative (I-DAIR), Geneva, Switzerland.

Karthiga Natarajan (K)

Infectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, Singapore.

Emily Devasagayam (E)

Department of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.

Evonne Tay (E)

Infectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, Singapore.

Abi Manesh (A)

Department of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.

George M Varghese (GM)

Department of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.

Ooriapadickal Cherian Abraham (OC)

Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.

Anand Zachariah (A)

Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.

Peiling Yap (P)

International Digital Health & AI Research Collaborative (I-DAIR), Geneva, Switzerland.

Dorothy Lall (D)

Department of Community Health, Christian Medical College Vellore - Chittoor Campus, Andhra Pradesh, India. Electronic address: dorothy.lall@cmcvellore.ac.in.

Angela Chow (A)

Infectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore. Electronic address: Angela_Chow@ttsh.com.sg.

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