Platinum-DNA Origami Hybrid Structures in Concentrated Hydrogen Peroxide.


Journal

Chemphyschem : a European journal of chemical physics and physical chemistry
ISSN: 1439-7641
Titre abrégé: Chemphyschem
Pays: Germany
ID NLM: 100954211

Informations de publication

Date de publication:
16 11 2023
Historique:
revised: 21 08 2023
received: 24 04 2023
medline: 23 11 2023
pubmed: 29 8 2023
entrez: 28 8 2023
Statut: ppublish

Résumé

The DNA origami technique allows fast and large-scale production of DNA nanostructures that stand out with an accurate addressability of their anchor points. This enables the precise organization of guest molecules on the surfaces and results in diverse functionalities. However, the compatibility of DNA origami structures with catalytically active matter, a promising pathway to realize autonomous DNA machines, has so far been tested only in the context of bio-enzymatic activity, but not in chemically harsh reaction conditions. The latter are often required for catalytic processes involving high-energy fuels. Here, we provide proof-of-concept data showing that DNA origami structures are stable in 5 % hydrogen peroxide solutions over the course of at least three days. We report a protocol to couple these to platinum nanoparticles and show catalytic activity of the hybrid structures. We suggest that the presented hybrid structures are suitable to realize catalytic nanomachines combined with precisely engineered DNA nanostructures.

Identifiants

pubmed: 37640688
doi: 10.1002/cphc.202300294
doi:

Substances chimiques

Hydrogen Peroxide BBX060AN9V
Platinum 49DFR088MY
DNA 9007-49-2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202300294

Subventions

Organisme : DFG
ID : 253407113
Organisme : Deutsche Forschungsgemeinschaft
ID : SFB1032
Organisme : DFG
ID : EXC 2089/1-390776260

Informations de copyright

© 2023 The Authors. ChemPhysChem published by Wiley-VCH GmbH.

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Auteurs

Mariana Alarcón-Correa (M)

Max Planck Institute for Medical Research, Jahnstr. 29, 69120, Heidelberg, Germany.
Institute for Molecular Systems Engineering and Advanced Materials, Heidelberg University, INF 225, 69120, Heidelberg, Germany.

Luzia Kilwing (L)

Faculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-University, Geschwister-Scholl-Platz 1, 80539, Munich, Germany.

Florian Peter (F)

Max Planck Institute for Medical Research, Jahnstr. 29, 69120, Heidelberg, Germany.
Institute for Molecular Systems Engineering and Advanced Materials, Heidelberg University, INF 225, 69120, Heidelberg, Germany.

Tim Liedl (T)

Faculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-University, Geschwister-Scholl-Platz 1, 80539, Munich, Germany.

Peer Fischer (P)

Max Planck Institute for Medical Research, Jahnstr. 29, 69120, Heidelberg, Germany.
Institute for Molecular Systems Engineering and Advanced Materials, Heidelberg University, INF 225, 69120, Heidelberg, Germany.

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