Balancing Redox Homeostasis to Improve l-Cysteine Production in
C. glutamicum
astaxanthin
autonomous bifunctional genetic switch
dynamic modulation
l-cysteine
Journal
Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755
Informations de publication
Date de publication:
20 Sep 2023
20 Sep 2023
Historique:
medline:
21
9
2023
pubmed:
5
9
2023
entrez:
5
9
2023
Statut:
ppublish
Résumé
l-Cysteine is a valuable sulfur-containing amino acid with applications across a wide range of fields. Recently, microbial fermentation has emerged as a method to produce l-cysteine. However, cellular redox stress from high levels of l-cysteine is a bottleneck for achieving efficient production. In this study, we aimed to facilitate l-cysteine biosynthesis by modulating cellular redox homeostasis through the introduction of the natural antioxidant astaxanthin in
Identifiants
pubmed: 37669547
doi: 10.1021/acs.jafc.3c03828
doi:
Substances chimiques
Cysteine
K848JZ4886
astaxanthine
8XPW32PR7I
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM