Comparing intralesional triamcinolone and verapamil-triamcinolone injections in keloids: A single-blinded randomised clinical trial.
injection
intralesional
keloids
triamcinolone
verapamil
wound
wound healing
Journal
International wound journal
ISSN: 1742-481X
Titre abrégé: Int Wound J
Pays: England
ID NLM: 101230907
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
revised:
28
06
2023
received:
26
05
2023
accepted:
01
07
2023
medline:
29
11
2023
pubmed:
6
9
2023
entrez:
6
9
2023
Statut:
ppublish
Résumé
In this clinical trial, we investigated the efficacy of two treatment methods for keloids resulting from surgical incisions: intralesional triamcinolone injections alone versus in combination with verapamil. Patients were divided into two groups: one received triamcinolone alone (Group T) and the other received a triamcinolone-verapamil blend (Group VT). Regular treatments were conducted until the keloids were nearly flat or for a maximum of eight sessions. Both groups showed significant improvements, but Group VT saw quicker resolution of skin redness and needed fewer sessions. Though the Vancouver Scar Scale (VSS) scores were generally similar across both groups, Group VT exhibited greater improvements, leading to lower final scores. The VT group also attained normal scar flexibility faster than the T group. These findings suggest that the combination of verapamil and triamcinolone provides a more effective treatment for keloids, thereby highlighting the potential of verapamil in scar reduction.
Identifiants
pubmed: 37670475
doi: 10.1111/iwj.14314
pmc: PMC10681400
doi:
Substances chimiques
Verapamil
CJ0O37KU29
Triamcinolone Acetonide
F446C597KA
Glucocorticoids
0
Types de publication
Randomized Controlled Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4166-4174Informations de copyright
© 2023 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.
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