Oxetanes in Drug Discovery Campaigns.
Journal
Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531
Informations de publication
Date de publication:
28 09 2023
28 09 2023
Historique:
medline:
29
9
2023
pubmed:
7
9
2023
entrez:
7
9
2023
Statut:
ppublish
Résumé
The oxetane ring is an emergent, underexplored motif in drug discovery that shows attractive properties such as low molecular weight, high polarity, and marked three-dimensionality. Oxetanes have garnered further interest as isosteres of carbonyl groups and as molecular tools to fine-tune physicochemical properties of drug compounds such as p
Identifiants
pubmed: 37676858
doi: 10.1021/acs.jmedchem.3c01101
pmc: PMC10544023
doi:
Substances chimiques
oxetane
I279Q16FU6
Ethers, Cyclic
0
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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