Cu, I-doped carbon dots as simulated nanozymes for the colorimetric detection of morphine in biological samples.


Journal

Analytical biochemistry
ISSN: 1096-0309
Titre abrégé: Anal Biochem
Pays: United States
ID NLM: 0370535

Informations de publication

Date de publication:
01 11 2023
Historique:
received: 27 06 2023
revised: 24 08 2023
accepted: 03 09 2023
medline: 19 9 2023
pubmed: 8 9 2023
entrez: 7 9 2023
Statut: ppublish

Résumé

As newly developed synthetic enzymes with exceptional catalytic capabilities and outstanding stability, nanozymes have drawn considerable interest in the realm of sensing. Using a simple hydrothermal process, iodine and copper-doped carbon dots (Cu,I-CDs) with simulated enzymes were fabricated in the current investigation. Cu,I-CDs demonstrate peroxidase-mimicking function together with high catalytic effectiveness due to aforementioned features. This led to generation of a colorimetric sensor for quick and accurate quantitative assessment of morphine (MOR). The outcomes showed the method's usefulness for the colorimetric detection of MOR. The linear range for MOR detection is 0.25-25 μg/mL having a reduced detection limit of 64 ng/mL. This sensor's successful use in the analysis of MOR in biological material is more noteworthy.

Identifiants

pubmed: 37678583
pii: S0003-2697(23)00278-6
doi: 10.1016/j.ab.2023.115313
pii:
doi:

Substances chimiques

Copper 789U1901C5
Carbon 7440-44-0
Morphine Derivatives 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

115313

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work, there is no professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the position presented in, or the review of, the manuscript entitled.

Auteurs

Qinhong Yin (Q)

Key Laboratory of Smart Drugs Control, Ministry of Education, Kunming, 650223, China; Yunnan Key Laboratory of Smart Drugs Control, Kunming, 650223, China; Yunnan Police College, Kunming, 650223, China.

Xiaolan Yang (X)

Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicina Endophytes, Yunnan Minzu University, Kunming, 650500, China.

Lihua Yang (L)

Key Laboratory of Smart Drugs Control, Ministry of Education, Kunming, 650223, China; Yunnan Key Laboratory of Smart Drugs Control, Kunming, 650223, China; Yunnan Police College, Kunming, 650223, China.

Dezhi Yang (D)

Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, China.

Yaling Yang (Y)

Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, China.

Yanqin Zhu (Y)

Research Center for Analysis and Measurement, Kunming University of Science and Technology, Kunming, 650093, China. Electronic address: 20070029@kust.edu.cn.

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Classifications MeSH