Undiagnosed Factor VII Deficiency in Cardiac Surgery Complicated by Bleeding: A Case Report.


Journal

A&A practice
ISSN: 2575-3126
Titre abrégé: A A Pract
Pays: United States
ID NLM: 101714112

Informations de publication

Date de publication:
01 Sep 2023
Historique:
medline: 11 9 2023
pubmed: 8 9 2023
entrez: 8 9 2023
Statut: epublish

Résumé

Rare bleeding disorders in the perioperative period call for targeted resuscitation strategies. Factor VII deficiency, for instance, is often corrected with exogenous administration of recombinant factor VIIa. This activated clotting factor, initially designed for patients with hemophilia A or B with factor inhibitors, is gaining popularity as a salvage therapy for severe and persistent traumatic and surgical bleeding. This article describes the management of a cardiothoracic surgical patient with undiagnosed isolated factor VII deficiency who experienced significant postoperative bleeding which subsided after the administration of recombinant factor VIIa. In this case, EXTEM failed to detect a clotting factor deficiency.

Identifiants

pubmed: 37681735
doi: 10.1213/XAA.0000000000001713
pii: 02054229-202309000-00001
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e01713

Informations de copyright

Copyright © 2023 International Anesthesia Research Society.

Déclaration de conflit d'intérêts

The authors declare no conflicts of interest.

Références

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Auteurs

Ziyad O Knio (ZO)

From the Department of Anesthesiology.

Mickey S Ising (MS)

Division of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Virginia.

Kenan W Yount (KW)

Division of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Virginia.

Kenichi Tanaka (K)

Department of Anesthesiology, University of Oklahoma, Oklahoma City, Oklahoma.

John S McNeil (JS)

From the Department of Anesthesiology.

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