Human CD34
CD34+ progenitor cells
Dendritic cells
Immunotherapy
NK cells
T cells
Vaccination
Journal
Cellular and molecular life sciences : CMLS
ISSN: 1420-9071
Titre abrégé: Cell Mol Life Sci
Pays: Switzerland
ID NLM: 9705402
Informations de publication
Date de publication:
20 Sep 2023
20 Sep 2023
Historique:
received:
29
05
2023
accepted:
11
08
2023
revised:
26
07
2023
medline:
21
9
2023
pubmed:
20
9
2023
entrez:
20
9
2023
Statut:
epublish
Résumé
Allogeneic stem cell transplantation (alloSCT) can be curative for hemato-oncology patients due to effective graft-versus-tumor immunity. However, relapse remains the major cause of treatment failure, emphasizing the need for adjuvant immunotherapies. In this regard, post-transplantation dendritic cell (DC) vaccination is a highly interesting strategy to boost graft-versus-tumor responses. Previously, we developed a clinically applicable protocol for simultaneous large-scale generation of end-stage blood DC subsets from donor-derived CD34
Identifiants
pubmed: 37728691
doi: 10.1007/s00018-023-04923-4
pii: 10.1007/s00018-023-04923-4
pmc: PMC10511603
doi:
Substances chimiques
Interleukin-12
187348-17-0
Antigens, CD34
0
Cell Adhesion Molecules
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
298Subventions
Organisme : KWF Kankerbestrijding
ID : 10351
Informations de copyright
© 2023. The Author(s).
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