Transgenic ferret models define pulmonary ionocyte diversity and function.
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
19
11
2022
accepted:
17
08
2023
medline:
4
10
2023
pubmed:
21
9
2023
entrez:
21
9
2023
Statut:
ppublish
Résumé
Speciation leads to adaptive changes in organ cellular physiology and creates challenges for studying rare cell-type functions that diverge between humans and mice. Rare cystic fibrosis transmembrane conductance regulator (CFTR)-rich pulmonary ionocytes exist throughout the cartilaginous airways of humans
Identifiants
pubmed: 37730992
doi: 10.1038/s41586-023-06549-9
pii: 10.1038/s41586-023-06549-9
pmc: PMC10533402
doi:
Substances chimiques
Cystic Fibrosis Transmembrane Conductance Regulator
126880-72-6
Forkhead Transcription Factors
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
857-867Subventions
Organisme : NHLBI NIH HHS
ID : P01 HL152960
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK054759
Pays : United States
Organisme : NIEHS NIH HHS
ID : P30 ES005605
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL165404
Pays : United States
Informations de copyright
© 2023. The Author(s).
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