Effect of neuromuscular blockade reversal on post-operative urinary retention following inguinal herniorrhaphy.
Anticholinesterase
Inguinal herniorrhaphy
Sugammadex
Urinary retention
Journal
Hernia : the journal of hernias and abdominal wall surgery
ISSN: 1248-9204
Titre abrégé: Hernia
Pays: France
ID NLM: 9715168
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
received:
24
05
2023
accepted:
27
07
2023
medline:
7
12
2023
pubmed:
22
9
2023
entrez:
22
9
2023
Statut:
ppublish
Résumé
This study aims to define the risk of post-operative urinary retention (POUR) following inguinal hernia repair in those that received sugammadex compared to anticholinesterase. Adults undergoing inguinal herniorrhaphy from January 2019 to July 2022 with at least 30-day follow-up receiving rocuronium or edrophonium and reversed with an anticholinesterase or sugammadex were included. 1-to-2 propensity score matched models were fitted to evaluate the treatment of effect of sugammadex vs. anticholinesterase on POUR, adjusting for patient comorbidities, ASA class, wound class, operative laterality, urgency of case, and open versus minimally invasive repair. 3345 patients were included in this study with 1101 (32.9%) receiving sugammadex for neuromuscular blockade reversal. The 30-day rate of POUR was 2.8%; 1.4% in the sugammadex and 4.4% in the anticholinesterase group. After propensity score matching, patients receiving sugammadex had significantly lower risk of POUR compared to anticholinesterase overall (OR 0.340, p < 0.001, 95% CI 0.198-0.585), in open (OR 0.296, p = 0.013, 95% CI 0.113-0.775) and minimally invasive cases (OR 0.36, p = 0.002, 95% CI 0.188-0.693), unilateral (OR 0.371, p = 0.001, 95% CI 0.203-0.681) and bilateral repairs (OR 0.25, p = 0.025, 95% CI 0.074-0.838), elective (OR 0.329, p < 0.001, 95% CI 0.185-0.584) and clean cases (OR 0.312, p < 0.001, 95% CI 0.176-0.553). The incidence of 30-day new onset POUR was 2.8%. Sugammadex was associated with significantly lower risk of POUR after inguinal herniorrhaphy compared to anticholinesterase overall and when stratifying by operative modality, laterality, and wound class.
Identifiants
pubmed: 37737305
doi: 10.1007/s10029-023-02857-1
pii: 10.1007/s10029-023-02857-1
doi:
Substances chimiques
Cholinesterase Inhibitors
0
Sugammadex
361LPM2T56
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1581-1586Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer-Verlag France SAS, part of Springer Nature.
Références
Bash LD, Turzhitsky V, Black W, Urman RD (2021) Neuromuscular blockade and reversal agent practice variability in the us inpatient surgical settings. Adv Ther 38(9):4736–4755. https://doi.org/10.1007/S12325-021-01835-2
doi: 10.1007/S12325-021-01835-2
pubmed: 34319550
pmcid: 8317140
Nag K, Singh D, Shetti A, Kumar H, Sivashanmugam T, Parthasarathy S (2013) Sugammadex: a revolutionary drug in neuromuscular pharmacology. Anesth Essays Res 7(3):302. https://doi.org/10.4103/0259-1162.123211
doi: 10.4103/0259-1162.123211
pubmed: 25885973
pmcid: 4173552
Kovac AL (2009) Sugammadex: the first selective binding reversal agent for neuromuscular block. J Clin Anesth 21(6):444–453. https://doi.org/10.1016/J.JCLINANE.2009.05.002
doi: 10.1016/J.JCLINANE.2009.05.002
pubmed: 19833281
Thilen SR, Weigel WA (2020) Sugammadex: a costly simple solution that is not really solving the problem. Anesth Analg 131(2):E73–E74. https://doi.org/10.1213/ANE.0000000000004761
doi: 10.1213/ANE.0000000000004761
pubmed: 32243289
Tammela T, Kontturi M, Lukkarinen O. (1986) Postoperative urinary retention. I. Incidence and predisposing factors. Scand J Urol Nephrol 20(3):197–201. https://doi.org/10.3109/00365598609024494
Lau H, Lam B (2004) Management of postoperative urinary retention: a randomized trial of in-out versus overnight catheterization. ANZ J Surg 74(8):658–661. https://doi.org/10.1111/J.1445-1433.2004.03116.X
doi: 10.1111/J.1445-1433.2004.03116.X
pubmed: 15315566
Petros JG, Rimm EB, Robillard RJ, Argy O (1991) Factors influencing postoperative urinary retention in patients undergoing elective inguinal herniorrhaphy. Am J Surg 161(4):431–433. https://doi.org/10.1016/0002-9610(91)91105-R
doi: 10.1016/0002-9610(91)91105-R
pubmed: 2035761
Baldini G, Bagry H, Aprikian A, Carli F (2009) Postoperative urinary retention: anesthetic and perioperative considerations. Anesthesiology 110(5):1139–1157. https://doi.org/10.1097/ALN.0B013E31819F7AEA
doi: 10.1097/ALN.0B013E31819F7AEA
pubmed: 19352147
Lamonerie L, Marret E, Deleuze A, Lembert N, Dupont M, Bonnet F (2004) Prevalence of postoperative bladder distension and urinary retention detected by ultrasound measurement. Br J Anaesth 92(4):544–546. https://doi.org/10.1093/BJA/AEH099
doi: 10.1093/BJA/AEH099
pubmed: 14977795
Colovic MB, Krstic DZ, Lazarevic-Pasti TD, Bondzic AM, Vasic VM (2013) Acetylcholinesterase inhibitors: pharmacology and toxicology. Curr Neuropharmacol 11(3):315–335. https://doi.org/10.2174/1570159X11311030006
doi: 10.2174/1570159X11311030006
pubmed: 24179466
pmcid: 3648782
Cao M, Wu X, Xu J (2022) A systematic review and meta-analysis of neostigmine for urinary retention after surgeries. Transl Androl Urol 11(2):190–201. https://doi.org/10.21037/TAU-22-16/COIF)
doi: 10.21037/TAU-22-16/COIF)
pubmed: 35280659
pmcid: 8899153
Low J, Escobar M, Baquero S, Goldman HS, Rosen G (2020) Glycopyrrolate and post-operative urinary retention: a narrative review. Cureus. https://doi.org/10.7759/CUREUS.11379
Valencia Morales DJ, Stewart BR, Heller SF et al (2021) Urinary retention following inguinal herniorrhaphy: role of neuromuscular blockade reversal. Surg Laparosc Endosc Percutan Tech 31(5):613–617. https://doi.org/10.1097/SLE.0000000000000962
doi: 10.1097/SLE.0000000000000962
pubmed: 34288639
Pavlin DJ, Rapp SE, Polissar NL, Malmgren JA, Koerschgen M, Keyes H (1998) Factors affecting discharge time in adult outpatients. Anesth Analg 87(4):816–826. https://doi.org/10.1097/00000539-199810000-00014
doi: 10.1097/00000539-199810000-00014
pubmed: 9768776
Broderick RC, Li JZ, Blitzer RR et al (2022) A steady stream of knowledge: decreased urinary retention after implementation of ERAS protocols in ambulatory minimally invasive inguinal hernia repair. Surg Endosc 36(9):6742–6750. https://doi.org/10.1007/S00464-021-08950-9
doi: 10.1007/S00464-021-08950-9
pubmed: 34982228
Grosse-Sundrup M, Henneman JP, Sandberg WS, et al. Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study. BMJ. 2012;345(7880). https://doi.org/10.1136/BMJ.E6329
Hurford WE, Welge JA, Eckman MH. Sugammadex versus neostigmine for routine reversal of rocuronium block in adult patients: a cost analysis. J Clin Anesth. 2020. https://doi.org/10.1016/J.JCLINANE.2020.110027