Developmental roles of natriuretic peptides and their receptors.
Cardiomyocyte
ESC
Neural crest
Neuron
Placode
Proliferation
Journal
Cells & development
ISSN: 2667-2901
Titre abrégé: Cells Dev
Pays: Netherlands
ID NLM: 101775611
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
received:
13
07
2023
revised:
18
09
2023
accepted:
19
09
2023
medline:
20
11
2023
pubmed:
25
9
2023
entrez:
24
9
2023
Statut:
ppublish
Résumé
Natriuretic peptides and their receptors are implicated in the physiological control of blood pressure, bone growth, and cardiovascular and renal homeostasis. They mediate their action through the modulation of intracellular levels of cGMP and cAMP, two second-messengers that have broad biological roles. In this review, we briefly describe the major players of this signaling pathway and their physiological roles in the adult, and discuss several reports describing their activity in the control of various aspects of embryonic development in several species. While the core components of this signaling pathway are well conserved, their functions have diverged in the embryo and the adult to control a diverse array of biological processes.
Identifiants
pubmed: 37742795
pii: S2667-2901(23)00054-2
doi: 10.1016/j.cdev.2023.203878
pii:
doi:
Substances chimiques
Natriuretic Peptides
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
203878Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no competing interests.