Supramolecular assembly of pyrene-DNA conjugates: influence of pyrene substitution pattern and implications for artificial LHCs.


Journal

Organic & biomolecular chemistry
ISSN: 1477-0539
Titre abrégé: Org Biomol Chem
Pays: England
ID NLM: 101154995

Informations de publication

Date de publication:
11 10 2023
Historique:
medline: 12 10 2023
pubmed: 26 9 2023
entrez: 26 9 2023
Statut: epublish

Résumé

The supramolecular self-assembly of pyrene-DNA conjugates into nanostructures is presented. DNA functionalized with different types of pyrene isomers at the 3'-end self-assemble into nano-objects. The shape of the nanostructures is influenced by the type of pyrene isomer appended to the DNA. Multilamellar vesicles are observed with the 1,6- and 1,8-isomers, whereas conjugates of the 2,7-isomer exclusively assemble into spherical nanoparticles. Self-assembled nano-spheres obtained with the 2,7-dialkynyl pyrene isomer were used for the construction of an artificial light-harvesting complex (LHC) in combination with Cy3 as the energy acceptor.

Identifiants

pubmed: 37750811
doi: 10.1039/d3ob01375h
pmc: PMC10566252
doi:

Substances chimiques

DNA 9007-49-2
Pyrenes 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

7908-7912

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Auteurs

Jan Thiede (J)

Department of Chemistry, Biochemistry, and Pharmaceutical Sciences, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland. robert.haener@unibe.ch.

Simon Rothenbühler (S)

Department of Chemistry, Biochemistry, and Pharmaceutical Sciences, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland. robert.haener@unibe.ch.

Ioan Iacovache (I)

Institute of Anatomy, University of Bern, Baltzerstrasse 2, CH-3012 Bern, Switzerland.

Simon M Langenegger (SM)

Department of Chemistry, Biochemistry, and Pharmaceutical Sciences, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland. robert.haener@unibe.ch.

Benoît Zuber (B)

Institute of Anatomy, University of Bern, Baltzerstrasse 2, CH-3012 Bern, Switzerland.

Robert Häner (R)

Department of Chemistry, Biochemistry, and Pharmaceutical Sciences, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland. robert.haener@unibe.ch.

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Classifications MeSH