Incidence of Intraoperative Vasoplegic Syndrome in Lung Transplantation.

Severe hypotension and low systemic vascular resistance in the setting of adequate cardiac output, known as "vasoplegic syndrome" (VS), is a physiologic disturbance reported in 9% to 44% of cardiac surgery patients. Although this phenomenon is well-documented in cardiac surgery, there are few studies on its occurrence in lung transplantation. The goal of this study was to characterize the incidence of VS in lung transplantation, as well as identify associated risk factors and outcomes. Retrospective study of single and bilateral lung transplants from April 2013 to September 2021. The study was conducted at an academic hospital. Patients ≥18 years of age who underwent lung transplantation. None. The authors defined VS as mean arterial pressure <65 mmHg, cardiac index ≥2.2 L/min/m The incidence of VS in lung transplantation is comparable to that of cardiac surgery. Interestingly, male sex and cystic fibrosis are strong risk factors. Identifying lung transplant recipients at increased risk of VS may be crucial to anticipating intraoperative complications.

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Declaration of Competing Interest E. Methangkool receives consulting fees from Edwards LifeSciences and author royalties from UpToDate, Inc.